Rockefeller University Press

Table II

Percent of LAMP-1/LAMP-2 Chimera Expressed at the Cell Surface

Chimera	Cell line	n^*	Average surface expression (%)^‡
	pool	3	7 ± 1
L/2c/2c	1-23	3	10 ± 2
	4	2	8
	5	2	4
	2-12	5	4 ± 1
	2-5	3	3 ± 2

L/2a/2a	pool	2	21
	6	3	14 ± 4
	8	3	14 ± 1
	10	3	9 ± 2
	19	4	26 ± 4
	20	3	21 ± 2
	23	3	17 ± 5

L/2a/2a	pool	3	26 ± 7
	6	3	13 ± 5
	9	3	17 ± 2
	11	3	25 ± 7
	14	3	28 ± 7
	20	5	39 ± 15
	24	4	27 ± 7

Chimera	Cell line	n^*	Average surface expression (%)^‡
	pool	3	7 ± 1
L/2c/2c	1-23	3	10 ± 2
	4	2	8
	5	2	4
	2-12	5	4 ± 1
	2-5	3	3 ± 2

L/2a/2a	pool	2	21
	6	3	14 ± 4
	8	3	14 ± 1
	10	3	9 ± 2
	19	4	26 ± 4
	20	3	21 ± 2
	23	3	17 ± 5

L/2a/2a	pool	3	26 ± 7
	6	3	13 ± 5
	9	3	17 ± 2
	11	3	25 ± 7
	14	3	28 ± 7
	20	5	39 ± 15
	24	4	27 ± 7

n represents the number of independent experiments in which each sample was assayed in triplicate.

‡

average per cell line ± standard deviation; calculated from ¹²⁵I-labeled mAb-CV24 binding to intact and permeabilized cells as described in Materials and Methods.

View Large

This Feature Is Available To Subscribers Only