Rockefeller University Press

Table 2.

Properties and occupancy of the two activity states in the Heeley et al. (2019) two-state model

States		I	A
ATPase		Low	High
Occupancy	+Tn −Ca	0.95 (0.95)	0.05 (0.05)
	+Tn +Ca	0.25 (0.8)	0.75 (0.2)
	+Myosin (ratio of myosin: actin, 1:7)	0.33 (0)	0.67 (1.0)

States		I	A
ATPase		Low	High
Occupancy	+Tn −Ca	0.95 (0.95)	0.05 (0.05)
	+Tn +Ca	0.25 (0.8)	0.75 (0.2)
	+Myosin (ratio of myosin: actin, 1:7)	0.33 (0)	0.67 (1.0)

The occupancy is based on the K_eq values given in Scheme 2 of Heeley et al. (2019) where K_eq is the equilibrium constant between the A and I states. The values in brackets are the occupancies predicted by the earlier two-state model of Hill et al. (1980).

View Large

This Feature Is Available To Subscribers Only