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Table 2.
Fitted parameters from nonstationary noise analysis
Constructat [Ca2+]iγPO max
  pA pS  
WT 2 µM 0.21 ± 0.013 2.63 ± 0.16 0.71 ± 0.022 
 1 mM 0.22 ± 0.0091 2.75 ± 0.11 0.87 ± 0.025 
E702Q 1 mM 0.19 ± 0.0094 2.38 ± 0.12 0.81 ± 0.018 
K588E 2 µM 0.084 ± 0.0057 1.05 ± 0.071 0.48 ± 0.055 
K588E/E702Q 1 mM 0.16 ± 0.014 2.00 ± 0.18 0.73 ± 0.025 
WT_WT 2 µM 0.15 ± 0.0046 1.88 ± 0.058 0.62 ± 0.039 
WT_E654Q 2 µM 0.17 ± 0.018 2.13 ± 0.23 0.66 ± 0.015 
 1 mM 0.196 ± 0.019 2.45 ± 0.24 0.81 ± 0.024 
WT_E702Q 2 µM 0.14 ± 0.0084 1.75 ± 0.11 0.50 ± 0.037 
Constructat [Ca2+]iγPO max
  pA pS  
WT 2 µM 0.21 ± 0.013 2.63 ± 0.16 0.71 ± 0.022 
 1 mM 0.22 ± 0.0091 2.75 ± 0.11 0.87 ± 0.025 
E702Q 1 mM 0.19 ± 0.0094 2.38 ± 0.12 0.81 ± 0.018 
K588E 2 µM 0.084 ± 0.0057 1.05 ± 0.071 0.48 ± 0.055 
K588E/E702Q 1 mM 0.16 ± 0.014 2.00 ± 0.18 0.73 ± 0.025 
WT_WT 2 µM 0.15 ± 0.0046 1.88 ± 0.058 0.62 ± 0.039 
WT_E654Q 2 µM 0.17 ± 0.018 2.13 ± 0.23 0.66 ± 0.015 
 1 mM 0.196 ± 0.019 2.45 ± 0.24 0.81 ± 0.024 
WT_E702Q 2 µM 0.14 ± 0.0084 1.75 ± 0.11 0.50 ± 0.037 

Presented as mean ± SEM calculated from fitted parameters from individual patches.

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