Rockefeller University Press

TABLE III.

Endogenous channel R_IV fingerprint is evident in SLC26A9 + ΔF508CFTR coexpressing HEK 293 cells

Construct	Time
	60 s	240 s	420 s
GFP(± fsk, n.s.)^a	1.27 ± 0.09	1.28 ± 0.09	1.29 ± 0.11
wtCFTR (no fsk)	1.27 ± 0.15	1.36 ± 0.11	nt^b
wtCFTR(3 min fsk at 240 s)	1.30 ± 0.05	0.98 ± 0.01^c	0.95 ± 0.01^c
SLC26A9 + ΔF508CFTR(3 min fsk at 240 s)	1.20 ± 0.05	1.20 ± 0.07	1.27 ± 0.08

Construct	Time
	60 s	240 s	420 s
GFP(± fsk, n.s.)^a	1.27 ± 0.09	1.28 ± 0.09	1.29 ± 0.11
wtCFTR (no fsk)	1.27 ± 0.15	1.36 ± 0.11	nt^b
wtCFTR(3 min fsk at 240 s)	1.30 ± 0.05	0.98 ± 0.01^c	0.95 ± 0.01^c
SLC26A9 + ΔF508CFTR(3 min fsk at 240 s)	1.20 ± 0.05	1.20 ± 0.07	1.27 ± 0.08

GFP-alone constructs did not demonstrate significant differences in R_IV in the presence or absence of forskolin stimulation, and the data are pooled.

nt, not tested.

P < 0.01 compared to same time point in other constructs.

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