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TABLE II

Fitted Parameters for Models in Figs. 6 and 7 


10-State
Cooperativity
Dimer-of-dimers
χ2 16.6 17.0 16.9 
Kab [ms−10.0157 0.016 0.0076 
Zab [e00.60 0.60 0.625 
Vab [mV] −78.2 −78.4 −78.4 
N/A 1.0 N/A 
γ [ms−10.40 0.29 0.27 
δ [ms−10.40 0.32 1.0 
1.57 1.55 1.53 

10-State
Cooperativity
Dimer-of-dimers
χ2 16.6 17.0 16.9 
Kab [ms−10.0157 0.016 0.0076 
Zab [e00.60 0.60 0.625 
Vab [mV] −78.2 −78.4 −78.4 
N/A 1.0 N/A 
γ [ms−10.40 0.29 0.27 
δ [ms−10.40 0.32 1.0 
1.57 1.55 1.53 

The only voltage-dependent transitions in the models are the rates determining the S4 movement: α = Kab exp(−Zab(V − Vab)/kT) and β = Kab exp(+Zab(V − Vab)/kT). The other rates are all voltage independent.

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