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TABLE III

Values of Other Parameters in the Multicompartment Simulations

A. Structural parameters (μm) 
    Length of the thin filament 1.0 
    Distance from z- to m-line 2.0 and 1.2 
    Radius of a myofibril 0.375 and 0.484 
B. Diffusion coefficients (16 °C) (10−6 cm2 s−1
    Free Ca2+ 
    ATP 1.4 
    Parvalbumin 0.15 
    Furaptra (protein-free) 1.59 
A. Structural parameters (μm) 
    Length of the thin filament 1.0 
    Distance from z- to m-line 2.0 and 1.2 
    Radius of a myofibril 0.375 and 0.484 
B. Diffusion coefficients (16 °C) (10−6 cm2 s−1
    Free Ca2+ 
    ATP 1.4 
    Parvalbumin 0.15 
    Furaptra (protein-free) 1.59 

The myofibrillar radii of 0.375 and 0.484 μm are for half-sarcomere lengths of 2.0 and 1.2 μm, respectively. The diffusion coefficients of ATP and furaptra apply to both the Ca2+-free and Ca2+-bound forms; the diffusion coefficient for parvalbumin applies to the Ca2+-bound, Mg2+-bound, and metal-free forms. Troponin, the SR Ca2+ pump, and protein-bound furaptra are considered to be nondiffusible.

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