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Table I.

Immunological data of patients

	Ig levels (g/liter)
	IgM	IgG	IgG1	IgG2	IgG3	IgG4	IgA	CD27⁺/CD19⁺ (%)^{^a}
P1^{^b}  (9 yr)	2.5^{^b}	3.5^{^b}	ND	ND	ND	ND	<0.06^{^b}	4
P2  (22 yr)	1	7.4	4.6	0.3	0.4	0.002	2.6	6
P3  (9 yr)	0.8	8.7	ND	ND	ND	ND	0.3	ND
P3  (17 yr)	2.5	8.9	6.2	0.1	0.3	0.001	0.8	23
Controls  (9 yr)	0.5–1.5	5.8–11.5					0.5–1.6	13–58
Controls  (17–22 yr)	0.5–2.1	6.6–12.7	>4	>0.6	>0.2	>0.01	0.7–3.4	13–58

	Ig levels (g/liter)
	IgM	IgG	IgG1	IgG2	IgG3	IgG4	IgA	CD27⁺/CD19⁺ (%)^{^a}
P1^{^b}  (9 yr)	2.5^{^b}	3.5^{^b}	ND	ND	ND	ND	<0.06^{^b}	4
P2  (22 yr)	1	7.4	4.6	0.3	0.4	0.002	2.6	6
P3  (9 yr)	0.8	8.7	ND	ND	ND	ND	0.3	ND
P3  (17 yr)	2.5	8.9	6.2	0.1	0.3	0.001	0.8	23
Controls  (9 yr)	0.5–1.5	5.8–11.5					0.5–1.6	13–58
Controls  (17–22 yr)	0.5–2.1	6.6–12.7	>4	>0.6	>0.2	>0.01	0.7–3.4	13–58

Bolded numbers indicate abnormal values. ND, not determined.

Gated on CD19⁺ B cells.

At age of immunodeficiency diagnosis before IgG substitution.