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Table I

Mutations in D4/S4-5 Producing Nonfunctional Channels

L1464 E (14)  L1472 D (14); K (16) 
L1465 E (10)  P1473 A (7); C (14); E (7); G (7) 
A1467 D (7)  A1474 L (21) 
L1468 E (65); K (50)  L1475 A (33); K (94) 
S1471 D (41); F (37); K (33); M (52)  N1477 C (8) 
L1464 E (14)  L1472 D (14); K (16) 
L1465 E (10)  P1473 A (7); C (14); E (7); G (7) 
A1467 D (7)  A1474 L (21) 
L1468 E (65); K (50)  L1475 A (33); K (94) 
S1471 D (41); F (37); K (33); M (52)  N1477 C (8) 

Number of analyzed cells is shown in parentheses. For each mutant, at least two independent clones were analyzed in at least two independent transfections.  

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