Skip to Main Content
Table I

The Mean Open and Closed Times, the Number of Events in Each State, and the Fractional Time of Each State of the Basal (Control), IBMX-, and Stretch-activated NSC Channels

OpenClosed
ShortLong
Mean times (ms)      
 Control 3.9 ± 1.1  2.0 ± 0.7  32.3 ± 10.0 
 IBMX 4.2 ± 2.0  2.3 ± 1.5  34.9 ± 13.0 
 Stretch 4.8 ± 2.0   2.4 ± 1.6  31.5 ± 15.1 
Fractional number of events (%)      
 Control 49.8 ± 3.2  11.2 ± 0.5  39.0 ± 0.6 
 IBMX 49.9 ± 0.4  32.6 ± 0.3*  17.6 ± 0.3* 
 Stretch 49.6 ± 0.4  32.9 ± 0.3*  17.5 ± 0.2* 
Fractional time (%)      
 Control 13.8 ± 4.9  1.6 ± 0.6  84.6 ± 5.7 
 IBMX 24.4 ± 10.9  7.6 ± 3.1*  68.0 ± 8.5* 
 Stretch 27.3 ± 6.3*  8.4 ± 4.8§  64.3 ± 10.2* 
OpenClosed
ShortLong
Mean times (ms)      
 Control 3.9 ± 1.1  2.0 ± 0.7  32.3 ± 10.0 
 IBMX 4.2 ± 2.0  2.3 ± 1.5  34.9 ± 13.0 
 Stretch 4.8 ± 2.0   2.4 ± 1.6  31.5 ± 15.1 
Fractional number of events (%)      
 Control 49.8 ± 3.2  11.2 ± 0.5  39.0 ± 0.6 
 IBMX 49.9 ± 0.4  32.6 ± 0.3*  17.6 ± 0.3* 
 Stretch 49.6 ± 0.4  32.9 ± 0.3*  17.5 ± 0.2* 
Fractional time (%)      
 Control 13.8 ± 4.9  1.6 ± 0.6  84.6 ± 5.7 
 IBMX 24.4 ± 10.9  7.6 ± 3.1*  68.0 ± 8.5* 
 Stretch 27.3 ± 6.3*  8.4 ± 4.8§  64.3 ± 10.2* 

These events were collected from ∼3-min records obtained from control (without IBMX treatment of application of stretch), IBMX-, and stretch-activated channels in cell-attached patches. The parameters in the IBMX-activated channel were not significantly different from those in the stretch-activated channel.  

*

P < 0.001;  

P < 0.05;  

§

P < 0.005. n = 7.  

Close Modal

or Create an Account

Close Modal
Close Modal