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Table I.

Immunofluorescence titers in mice immunized with αDEC-CS antibody


Primea

Boostb

Reciprocal IFA titerc
PBS αDEC-CS <600 
αDEC-CS+anti-CD40+poly I:C αDEC-CS 106,920 (±53,237) 
anti-CD40+poly I:C αDEC-CS 900 (±600) 
Irradiated sporozoites
 

 
4,500 (±1,800)
 

Primea

Boostb

Reciprocal IFA titerc
PBS αDEC-CS <600 
αDEC-CS+anti-CD40+poly I:C αDEC-CS 106,920 (±53,237) 
anti-CD40+poly I:C αDEC-CS 900 (±600) 
Irradiated sporozoites
 

 
4,500 (±1,800)
 
a

Groups of four mice were primed with 10 μg αDEC-CS plus maturation stimulus, maturation stimulus alone, 7.5 × 104 irradiated sporozoites, or PBS.

b

Mice were boosted with 10 μg αDEC-CS or nothing.

c

Immunofluorescence assay was performed 7 d after boost using serial dilutions of serum from individual mice. Results are depicted as the mean of reciprocal titers ±SD.

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