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Table II.

Association of the CCR5Δ32 allele with symptomatic WNV infection in Arizona and Colorado



CCR5Δ32 Genotype, n (%)
All racial groups
Self-reporting Caucasians
Cohort
+/+
+/Δ32
Δ32/Δ32
+/+
+/Δ32
Δ32/Δ32
Arizona WNV+ 205 (83.0) 31 (12.6) 11 (4.5) 115 (80.4) 22 (15.4) 6 (4.2) 
Colorado WNV+ 111 (75.0) 31 (20.9) 6 (4.1) 49 (68.1) 17 (23.6) 6 (8.3) 
Combined WNV+ 316 (80.0) 62 (15.7) 17 (4.3) 164 (76.3) 39 (18.1) 12 (5.6) 
Arizona WNV− 125 (86.2) 19 (13.1) 1 (0.7) 16 (84.2) 3 (15.8) 0 (0) 
RBD
 
N/A
 
N/A
 
N/A
 
1102 (83.6)
 
203 (15.4)
 
13 (1.0)
 


CCR5Δ32 Genotype, n (%)
All racial groups
Self-reporting Caucasians
Cohort
+/+
+/Δ32
Δ32/Δ32
+/+
+/Δ32
Δ32/Δ32
Arizona WNV+ 205 (83.0) 31 (12.6) 11 (4.5) 115 (80.4) 22 (15.4) 6 (4.2) 
Colorado WNV+ 111 (75.0) 31 (20.9) 6 (4.1) 49 (68.1) 17 (23.6) 6 (8.3) 
Combined WNV+ 316 (80.0) 62 (15.7) 17 (4.3) 164 (76.3) 39 (18.1) 12 (5.6) 
Arizona WNV− 125 (86.2) 19 (13.1) 1 (0.7) 16 (84.2) 3 (15.8) 0 (0) 
RBD
 
N/A
 
N/A
 
N/A
 
1102 (83.6)
 
203 (15.4)
 
13 (1.0)
 

All patients from Arizona and Colorado had symptoms for which WNV infection was considered as the underlying cause. WNV+, WNV seropositive; WNV−, WNV seronegative; +, wild-type CCR5 allele; Δ32, CCR5Δ32 allele; RBD, random blood donors; N/A, not applicable.

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