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Table II

Allele and genotype frequencies of FAS and FASL among controls and cases and their association with cervical cancer


Genotype

Controls (n = 615)

Patients (n = 314)

ORa (95% CI)

P

 
No. (%)
 
No. (%)
 

 

 
FAS –1377G→A     
GG 282 (45.8) 144 (45.9) reference  
AG 277 (45.1) 144 (45.9) 1.01 (0.75–1.37) 0.934 
AA 56 (9.1) 26 (8.2) 0.87 (0.51–1.49) 0.617 
A allele frequency 0.317 0.312   
FAS –670A→G     
AA 268 (43.6) 138 (43.9) reference  
AG 272 (44.2) 144 (45.9) 1.09 (0.81–1.47) 0.850 
GG 75 (12.2) 32 (10.2) 0.85 (0.53–1.36) 0.425 
G allele frequency 0.343 0.332   
FASL –844T→C     
TT 40 (6.5) 10 (3.2) reference  
CT 291 (47.3) 111 (35.3) 1.68 (0.78–3.66) 0.187 
CC 284 (46.2) 193 (61.5) 3.05 (1.43–6.52) 0.004 
C allele frequency
 
0.699
 
0.792
 

 

 

Genotype

Controls (n = 615)

Patients (n = 314)

ORa (95% CI)

P

 
No. (%)
 
No. (%)
 

 

 
FAS –1377G→A     
GG 282 (45.8) 144 (45.9) reference  
AG 277 (45.1) 144 (45.9) 1.01 (0.75–1.37) 0.934 
AA 56 (9.1) 26 (8.2) 0.87 (0.51–1.49) 0.617 
A allele frequency 0.317 0.312   
FAS –670A→G     
AA 268 (43.6) 138 (43.9) reference  
AG 272 (44.2) 144 (45.9) 1.09 (0.81–1.47) 0.850 
GG 75 (12.2) 32 (10.2) 0.85 (0.53–1.36) 0.425 
G allele frequency 0.343 0.332   
FASL –844T→C     
TT 40 (6.5) 10 (3.2) reference  
CT 291 (47.3) 111 (35.3) 1.68 (0.78–3.66) 0.187 
CC 284 (46.2) 193 (61.5) 3.05 (1.43–6.52) 0.004 
C allele frequency
 
0.699
 
0.792
 

 

 
a

Data were calculated by unconditional logistic regression, adjusting for age and smoking status.

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