Skip to Main Content
Table I

Endomucin marks LTR-HSCs in AGM





Percent chimerism for donor cells
Cell type
Cells permouse
Engrafted mice
Total
Myeloidcell
B cell
T cell
E10.5 AGM       
4541E+ 750 0/4 
4541+E+ 750 4/4 0.4 ± 0.3 0.11 ± 0.02 1.4 ± 0 
4541+E 750 0/4 
4541E 750 0/4 
45+ 750 0/5 
E11.5 AGM (Exp.-1)       
4541 3,615 0/5 
4541+E+ 122 0/3 
4541+E 172 0/5 
45+E+ 112 1/3 17.5 1.72 46.9 6.56 
45+E 500 0/5 
E11.5 AGM (Exp.-2)       
Whole 105 2/4 14.9/67.8 0.6/71.9 30.4/67.8 35.1/60.8 
45E+ 1,829 0/4 
45E 4.5 × 104 0/4 
45+E+ 289 1/3 18.3 0.8 27.2 20.4 
45+E
 
6,000
 
0/4
 
-
 
-
 
-
 
-
 




Percent chimerism for donor cells
Cell type
Cells permouse
Engrafted mice
Total
Myeloidcell
B cell
T cell
E10.5 AGM       
4541E+ 750 0/4 
4541+E+ 750 4/4 0.4 ± 0.3 0.11 ± 0.02 1.4 ± 0 
4541+E 750 0/4 
4541E 750 0/4 
45+ 750 0/5 
E11.5 AGM (Exp.-1)       
4541 3,615 0/5 
4541+E+ 122 0/3 
4541+E 172 0/5 
45+E+ 112 1/3 17.5 1.72 46.9 6.56 
45+E 500 0/5 
E11.5 AGM (Exp.-2)       
Whole 105 2/4 14.9/67.8 0.6/71.9 30.4/67.8 35.1/60.8 
45E+ 1,829 0/4 
45E 4.5 × 104 0/4 
45+E+ 289 1/3 18.3 0.8 27.2 20.4 
45+E
 
6,000
 
0/4
 
-
 
-
 
-
 
-
 

Results of competitive adult BM repopulation assays using E10.5 and E11.5 AGM cells. The indicated number of cells from each subpopulation (B6-Ly5.2) was mixed with 1 × 105 B6-Ly5.1 competitor cells. The mixture was injected directly into the BM (intra-BM transplantation) of lethally irradiated B6-Ly5.1 recipient mice. An additional 2 × 105 B6-Ly5.1 competitor cells were injected intravenously. E, Endomucin.

Close Modal

or Create an Account

Close Modal
Close Modal