Skip to Main Content
Table I.

Thymus Cell Counts, Percentages, and Absolute Cell Numbers of CD4+CD8+icTCRβ+ or CD4+CD8+icTCRβ Cells in Wild Type, Ptenflox/floxLck-Cre, CD3γ−/−, and Ptenflox/floxLck-Cre × CD3γ−/− Mice


Age

Genotype

n

Thymus
 cellularity

CD4+CD8+
 total

CD4+CD8+
 icTCRβ+

CD4+CD8+
 icTCRβ+

CD4+CD8+
 icTCRβ
wk
 

 

 
no. × 10−6
 
%
 
%
 
no. × 10−6
 
no. × 10−6
 
1
 
wild type
 
ND
 
ND
 
ND
 
ND
 
ND
 
ND
 

 
Pten−/−
 
ND
 
ND
 
ND
 
ND
 
ND
 
ND
 

 
CD3γ−/−
 
9
 
4.4 ± 1.4
 
12 ± 4.4
 
88 ± 2.7
 
0.48 ± 0.26
 
0.07 ± 0.04
 

 
Pten−/− × CD3γ−/−
 
1
 
3.4
 
26
 
46
 
0.40
 
0.47
 
2
 
wild type
 
7
 
96 ± 20
 
81 ± 5.6
 
99 ± 0.1
 
80 ± 15
 
0.3 ± 0.1
 

 
Pten−/−
 
4
 
108 ± 10
 
81 ± 6.8
 
99 ± 0.1
 
88 ± 13
 
0.3 ± 0.1
 

 
CD3γ−/−
 
7
 
12 ± 2.4
 
8.7 ± 7.7
 
58 ± 5.1
 
0.64 ± 0.56
 
0.44 ± 0.41
 

 
Pten−/− × CD3γ−/−
 
3
 
56 ± 23
 
83 ± 1.5
 
27 ± 9.1
 
13 ± 7.1
 
34 ± 16
 
4
 
wild type
 
3
 
144 ± 32
 
81 ± 0.9
 
99 ± 0.9
 
114 ± 23
 
2.0 ± 1.2
 

 
Pten−/−
 
2
 
162 ± 29
 
78 ± 3.3
 
99 ± 0.4
 
124 ± 27
 
1.6 ± 0.8
 

 
CD3γ−/−
 
4
 
5.4 ± 0.3
 
2.0 ± 0.7
 
70 ± 7.0
 
0.08 ± 0.03
 
0.03 ± 0.003
 

 
Pten−/− × CD3γ−/−
 
3
 
180 ± 4.0
 
72 ± 5.0
 
23 ± 3.0
 
30 ± 5.3
 
100 ± 0.9
 

Age

Genotype

n

Thymus
 cellularity

CD4+CD8+
 total

CD4+CD8+
 icTCRβ+

CD4+CD8+
 icTCRβ+

CD4+CD8+
 icTCRβ
wk
 

 

 
no. × 10−6
 
%
 
%
 
no. × 10−6
 
no. × 10−6
 
1
 
wild type
 
ND
 
ND
 
ND
 
ND
 
ND
 
ND
 

 
Pten−/−
 
ND
 
ND
 
ND
 
ND
 
ND
 
ND
 

 
CD3γ−/−
 
9
 
4.4 ± 1.4
 
12 ± 4.4
 
88 ± 2.7
 
0.48 ± 0.26
 
0.07 ± 0.04
 

 
Pten−/− × CD3γ−/−
 
1
 
3.4
 
26
 
46
 
0.40
 
0.47
 
2
 
wild type
 
7
 
96 ± 20
 
81 ± 5.6
 
99 ± 0.1
 
80 ± 15
 
0.3 ± 0.1
 

 
Pten−/−
 
4
 
108 ± 10
 
81 ± 6.8
 
99 ± 0.1
 
88 ± 13
 
0.3 ± 0.1
 

 
CD3γ−/−
 
7
 
12 ± 2.4
 
8.7 ± 7.7
 
58 ± 5.1
 
0.64 ± 0.56
 
0.44 ± 0.41
 

 
Pten−/− × CD3γ−/−
 
3
 
56 ± 23
 
83 ± 1.5
 
27 ± 9.1
 
13 ± 7.1
 
34 ± 16
 
4
 
wild type
 
3
 
144 ± 32
 
81 ± 0.9
 
99 ± 0.9
 
114 ± 23
 
2.0 ± 1.2
 

 
Pten−/−
 
2
 
162 ± 29
 
78 ± 3.3
 
99 ± 0.4
 
124 ± 27
 
1.6 ± 0.8
 

 
CD3γ−/−
 
4
 
5.4 ± 0.3
 
2.0 ± 0.7
 
70 ± 7.0
 
0.08 ± 0.03
 
0.03 ± 0.003
 

 
Pten−/− × CD3γ−/−
 
3
 
180 ± 4.0
 
72 ± 5.0
 
23 ± 3.0
 
30 ± 5.3
 
100 ± 0.9
 
Close Modal

or Create an Account

Close Modal
Close Modal