Rockefeller University Press

Table 1

A^u Binding Affinity Correlates Inversely with EAE Induction

Peptide	Sequence	Relative binding affinity for A^u	Incidence of EAE
			%
4Lys	AcASQKRPSQR	<0.00001	60
4Ala	AcASQARPSQR	0.01	10
4Val	AcASQVRPSQR	0.2	0
4Tyr	AcASQYRPSQR	1	0

Peptide	Sequence	Relative binding affinity for A^u	Incidence of EAE
			%
4Lys	AcASQKRPSQR	<0.00001	60
4Ala	AcASQARPSQR	0.01	10
4Val	AcASQVRPSQR	0.2	0
4Tyr	AcASQYRPSQR	1	0

Binding affinities of peptides for A^u were assessed as described previously (reference 24). Incidence of EAE represents cumulative data from experiments shown in Fig. 1D and Fig. E.

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