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Table 1

Au Binding Affinity Correlates Inversely with EAE Induction

PeptideSequenceRelative binding affinity for AuIncidence of EAE
   
4Lys AcASQKRPSQR <0.00001 60 
4Ala AcASQARPSQR 0.01 10 
4Val AcASQVRPSQR 0.2 
4Tyr AcASQYRPSQR 
PeptideSequenceRelative binding affinity for AuIncidence of EAE
   
4Lys AcASQKRPSQR <0.00001 60 
4Ala AcASQARPSQR 0.01 10 
4Val AcASQVRPSQR 0.2 
4Tyr AcASQYRPSQR 

Binding affinities of peptides for Au were assessed as described previously (reference 24). Incidence of EAE represents cumulative data from experiments shown in Fig. 1D and Fig. E.

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