Rockefeller University Press

Table 2

Frequency of CD95 Mutations in Human B Cell Subsets; Single-Cell Analysis from Donors II–VII

	Mutations per cell		Mutation frequency
B cell subset; phenotype	5′ region	Exon IX	5′ region	Exon IX
			× 10⁻⁴/bp
Naive; IgD⁺IgM⁺CD27⁻	1/48	0/66	0.3	<0.2
GC; CD38⁺CD77⁺	12/60	2/45	2.5	0.7
anti-CD95–resistant GC; annexin V–negative, CD38⁺	4/10	12/22	5.0	7.7
Memory; IgD⁻CD20⁺CD27⁺	6/17	0/33	3.1	<0.4

	Mutations per cell		Mutation frequency
B cell subset; phenotype	5′ region	Exon IX	5′ region	Exon IX
			× 10⁻⁴/bp
Naive; IgD⁺IgM⁺CD27⁻	1/48	0/66	0.3	<0.2
GC; CD38⁺CD77⁺	12/60	2/45	2.5	0.7
anti-CD95–resistant GC; annexin V–negative, CD38⁺	4/10	12/22	5.0	7.7
Memory; IgD⁻CD20⁺CD27⁺	6/17	0/33	3.1	<0.4