Rockefeller University Press

Table I.

Cellular Subset Distribution in Different Chimeric and BAFF^−/− Mice

	WT→KO	KO→WT	WT→WT	KO
Total	35.21 ± 4.95^{^a}	91.75 ± 10.9^{^b}	86.76 ± 5.98^{^b}	44.50 ± 9.32^{^a}
B220⁺	14.28 ± 1.78^{^a}	64.26 ± 5.01^{^b}	50.15 ± 4.06^{^b}	8.65 ± 0.78^{^a}
CD4⁺ and CD8⁺	16.47 ± 2.40	25.82 ± 2.52	23.94 ± 1.60	21.93 ± 2.13
CD11c⁺	0.54 ± 0.10^{^a}	1.30 ± 0.25^{^b}	1.16 ± 0.15^{^b}	0.44 ± 0.02^{^a}
CD11b⁺	2.10 ± 0.66	1.78 ± 0.22	1.70 ± 0.17	1.52 ± 0.26
FO (CD21^interm CD23^high)	8.04 ± 1.03^{^a}^,^{^b}	45.45 ± 3.82^{^b}	38.93 ± 4.18^{^b}	1.70 ± 0.39^{^a}
MZ (CD21^high CD23^low)	0.41 ± 0.12^{^a}	3.41 ± 0.42^{^b}	3.68 ± 0.37^{^b}	0.14 ± 0.04^{^a}
NF (CD21⁻ CD23⁻)	2.89 ± 0.53^{^a}	10.79 ± 1.87	4.99 ± 0.56	4.58 ± 1.55

	WT→KO	KO→WT	WT→WT	KO
Total	35.21 ± 4.95^{^a}	91.75 ± 10.9^{^b}	86.76 ± 5.98^{^b}	44.50 ± 9.32^{^a}
B220⁺	14.28 ± 1.78^{^a}	64.26 ± 5.01^{^b}	50.15 ± 4.06^{^b}	8.65 ± 0.78^{^a}
CD4⁺ and CD8⁺	16.47 ± 2.40	25.82 ± 2.52	23.94 ± 1.60	21.93 ± 2.13
CD11c⁺	0.54 ± 0.10^{^a}	1.30 ± 0.25^{^b}	1.16 ± 0.15^{^b}	0.44 ± 0.02^{^a}
CD11b⁺	2.10 ± 0.66	1.78 ± 0.22	1.70 ± 0.17	1.52 ± 0.26
FO (CD21^interm CD23^high)	8.04 ± 1.03^{^a}^,^{^b}	45.45 ± 3.82^{^b}	38.93 ± 4.18^{^b}	1.70 ± 0.39^{^a}
MZ (CD21^high CD23^low)	0.41 ± 0.12^{^a}	3.41 ± 0.42^{^b}	3.68 ± 0.37^{^b}	0.14 ± 0.04^{^a}
NF (CD21⁻ CD23⁻)	2.89 ± 0.53^{^a}	10.79 ± 1.87	4.99 ± 0.56	4.58 ± 1.55

Significantly (P < 0.01) different from the WT→WT mice.

Significantly (P < 0.01) different from the KO mice.

8–12 wk after the reconstitution of lethally irradiated (950 rads) mice with the BM, spleen cells were analyzed by FACS^®. Mean cell numbers ×10⁶ ± SD for each population are derived from 8–14 mice per group.

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