Skip to Main Content
Table 1

Summary of VH186.2 Sequences from NP-specific IgG1+ B Cells at Day 42 after Immunization

Control CD38+bcl-2 CD38+
Single cells 74 38 
PCR+ 31 32 
VH186.2+ 26 24 
R/S ratio   
CDR1+2 4.0 2.9 
FW1−3 2.7 1.8 
Position 33 W→L 62% 13% 
Mutation average 4.6 2.7 
Range 0–14 0–12 
Control CD38+bcl-2 CD38+
Single cells 74 38 
PCR+ 31 32 
VH186.2+ 26 24 
R/S ratio   
CDR1+2 4.0 2.9 
FW1−3 2.7 1.8 
Position 33 W→L 62% 13% 
Mutation average 4.6 2.7 
Range 0–14 0–12 

R/S ratio, ratio of replacement to silent mutations.

Close Modal

or Create an Account

Close Modal
Close Modal