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Table 1

Cell Numbers in WAS−/− Mice

TissueTotal no. of cells (×10−6) ± SD
+/+WAS−/−
Thymus 116.0 ± 16.6 43.6 ± 12.5 
Lymph nodes 49.3 ± 10.0 24.8 ± 2.7 
Spleen 47.0 ± 7.8 20.4 ± 2.8 
Bone marrow 10.3 ± 1.4 10.0 ± 2.6 
Platelets 616.0 ± 65.4 377.8 ± 94.2 
TissueTotal no. of cells (×10−6) ± SD
+/+WAS−/−
Thymus 116.0 ± 16.6 43.6 ± 12.5 
Lymph nodes 49.3 ± 10.0 24.8 ± 2.7 
Spleen 47.0 ± 7.8 20.4 ± 2.8 
Bone marrow 10.3 ± 1.4 10.0 ± 2.6 
Platelets 616.0 ± 65.4 377.8 ± 94.2 

Total thymocytes, total mesenteric, axillary and inguinal lymph node T cells, total splenocytes, and bone marrow cells (one femur) from wild-type (+/+; n = 4) and WAS−/− (n = 4) mice were isolated and counted; blood platelet count (cells/ml) was determined from tail-bled wild-type and WAS−/− mice (n = 5).

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