Rockefeller University Press

Table 1

Insulitis Scores in NOD-RIP-B7-1/β₂m^null and NOD-RIP-B7-1/CD4 −/− Mice

Mice	Insulitis score
Mice	0	1	2	3	4
NOD-RIP-B7-1/β₂m^null	86
NOD-RIP-B7-1/CD4 −/−		6	23	13	35

Mice	Insulitis score
Mice	0	1	2	3	4
NOD-RIP-B7-1/β₂m^null	86
NOD-RIP-B7-1/CD4 −/−		6	23	13	35

Insulitis of individual islets was assessed according to the scale of 0 to 4 as follows: 0, no insulitis; 1, periinsulitis; 2, periinsulitis with some insulitis; 3, >50% of the islet infiltrated; 4, complete islet destruction. Insulitis in NOD-RIP-B7-1/β₂m^null mice was assessed in 86 islets from 10 nondiabetic mice. Insulitis in NOD-RIP-B7-1/CD4 −/− mice was assessed in 77 islets from 9 nondiabetic mice.

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