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Table 2

Negative Control Littermates of Transgenic Mice Examined

AnimalSexAgeSerum IFN-γIIFCLKidney DIF
      pg/ml       
C1   12    −  −  − 
C2   10    −  −  − 
C3    3    −  −   
C4   10    −  −  − 
C5   13  UN  −  −  − 
C6   13  UN  −  −  − 
C7   13     −   
C8   12  UN    −   
C9   11  UN    −   
C10    4  UN    −   
C11    7      −   
C12    7      −   
AnimalSexAgeSerum IFN-γIIFCLKidney DIF
      pg/ml       
C1   12    −  −  − 
C2   10    −  −  − 
C3    3    −  −   
C4   10    −  −  − 
C5   13  UN  −  −  − 
C6   13  UN  −  −  − 
C7   13     −   
C8   12  UN    −   
C9   11  UN    −   
C10    4  UN    −   
C11    7      −   
C12    7      −   

Age is quoted in months. M, male; F, female; IIF, indirect immunofluorescence on normal mouse skin/esophagus; DIF, direct immunofluorescence; CL, testing for anti-dsDNA on C. luciliae; UN, undetectable. Absence of glomerular Ig deposits was confirmed by electron microscopy in mice C4 and C5.  

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