Skip to Main Content
Table 3

Effect of Anti–TNF-α on Visceral Infection in GKO Mice

Treatment during weeks 8–12Liver Parasite Burden (LDU)
Week 8Week 12
None (control)  9,788 ± 579   4,187 ± 636 
Normal serum     3,943 ± 469 
Anti–TNF-α    10,202 ± 1,361 
Treatment during weeks 8–12Liver Parasite Burden (LDU)
Week 8Week 12
None (control)  9,788 ± 579   4,187 ± 636 
Normal serum     3,943 ± 469 
Anti–TNF-α    10,202 ± 1,361 

Starting 8 wk after infection, GKO mice were injected twice-weekly with either normal rabbit serum or anti–TNF-α antiserum. Results are mean LDU ± SEM from two experiments with 5–6 mice per group. P <0.002 for anti–TNF-α–treated group versus untreated and normal saline-treated mice.  

Close Modal

or Create an Account

Close Modal
Close Modal