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Table 1

Distribution of Phenotypes of Hematopoietic Cells Isolated from the Spleen and Liver

OrganMice
MarkerNontransgenicsIL-6RIL-6IL-6–sIL-6R
Spleen  GR1     10.0  10.5  10.7    23.6 
  MAC-1     12     14        6.7    21.6 
  SCA-1     20     21  23.4    42 
  B220     14     15    35    36 
  CD8          2.15     2.11     2.34     3.2 
  CD4          6.8     8.8    3.8     5.8 
           
Liver  GR1  0.003     0.004  −     1.14 
  MAC-1      −     0.006    0.08     1.04 
  SCA-1   −  −  −  0.932 
  B220          0.001     0.002    0.09  0.665 
OrganMice
MarkerNontransgenicsIL-6RIL-6IL-6–sIL-6R
Spleen  GR1     10.0  10.5  10.7    23.6 
  MAC-1     12     14        6.7    21.6 
  SCA-1     20     21  23.4    42 
  B220     14     15    35    36 
  CD8          2.15     2.11     2.34     3.2 
  CD4          6.8     8.8    3.8     5.8 
           
Liver  GR1  0.003     0.004  −     1.14 
  MAC-1      −     0.006    0.08     1.04 
  SCA-1   −  −  −  0.932 
  B220          0.001     0.002    0.09  0.665 

Freshly isolated cells obtained from organs as indicated in the table were subjected to FACS® analysis. Values are expressed as total numbers of cells × 106 per organ. One representative experiment out of three is shown.  

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