Skip to Main Content
Table 2

Protection of Gerbils from Amebic Liver Abscess by Vaccination with Recombinantly Expressed Fragments of the 170-kD Lectin

Vaccine groupNo. of gerbils with liver abscess/ No. of gerbils challengedPercent protectedSize of liver abscesses
      mm mean ± SD 
Buffer  17/17 (5/5, 5/5, 7/7)   0.0  6 ± 2 
r170CP  15/16 (3/4, 5/5, 6/6)   6.7  9 ± 3* 
r170PR  10/16 (3/5, 3/4, 4/7)  37.5 (P <0.05)  3 ± 2* 
r170CR1  8/9 (4/5, 4/4)  11.1  5 ± 3 
r170CR2  6/16 (2/5, 1/4, 3/7)  62.5 (P <0.001)  3 ± 1* 
Vaccine groupNo. of gerbils with liver abscess/ No. of gerbils challengedPercent protectedSize of liver abscesses
      mm mean ± SD 
Buffer  17/17 (5/5, 5/5, 7/7)   0.0  6 ± 2 
r170CP  15/16 (3/4, 5/5, 6/6)   6.7  9 ± 3* 
r170PR  10/16 (3/5, 3/4, 4/7)  37.5 (P <0.05)  3 ± 2* 
r170CR1  8/9 (4/5, 4/4)  11.1  5 ± 3 
r170CR2  6/16 (2/5, 1/4, 3/7)  62.5 (P <0.001)  3 ± 1* 
*

Significant difference from buffer control (P <0.05) as determined by Fisher's exact test.  

Close Modal

or Create an Account

Close Modal
Close Modal