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Table I

Body Weight of Mutant Mice and Wild-Type Controls

Age*SexMean weights ± SD (number of mice examined)
Wild-typeHeterozygoteHomozygote
      g   
8 d      5.1 ± 0.8 (28)   4.8 ± 0.9 (28)   3.7 ± 0.7 (17) 
8 wk  male  23.9 ± 2.7 (7)  25.0 ± 2.8 (18)  20.1 ± 2.6 (7)§ 
  female   19.2 ± 1.4 (13)  19.4 ± 2.5 (21)  16.0 ± 3.0 (7)§ 
12 wk  male  26.9 ± 3.2 (7)  28.2 ± 3.8 (18)  21.2 ± 2.2 (7) 
  female   22.0 ± 1.8 (10)  21.4 ± 2.9 (20)  17.9 ± 2.7 (5)§ 
Age*SexMean weights ± SD (number of mice examined)
Wild-typeHeterozygoteHomozygote
      g   
8 d      5.1 ± 0.8 (28)   4.8 ± 0.9 (28)   3.7 ± 0.7 (17) 
8 wk  male  23.9 ± 2.7 (7)  25.0 ± 2.8 (18)  20.1 ± 2.6 (7)§ 
  female   19.2 ± 1.4 (13)  19.4 ± 2.5 (21)  16.0 ± 3.0 (7)§ 
12 wk  male  26.9 ± 3.2 (7)  28.2 ± 3.8 (18)  21.2 ± 2.2 (7) 
  female   22.0 ± 1.8 (10)  21.4 ± 2.9 (20)  17.9 ± 2.7 (5)§ 
*

 Number of postnatal days or weeks at time of measurements.  

 Different from value for wild-type mice at P < 0.000001, at P < 0.05, 

§

and at P < 0.005. 

  Student's t test was used to determine the significance of the difference.  

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