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Journal Articles

Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics

Cecile Terrenoire, Kai Wang, Kelvin W. Chan Tung, Wendy K. Chung, Robert H. Pass, Jonathan T. Lu, Jyh-Chang Jean, Amel Omari, Kevin J. Sampson, Darrell N. Kotton, Gordon Keller, Robert S. Kass
Journal: Journal of General Physiology
J Gen Physiol (2012) 141 (1): 61–72.
https://doi.org/10.1085/jgp.201210899
Published: 31 December 2012
View article titled, Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics
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Journal Articles

Translation of myelin basic protein mRNA in oligodendrocytes is regulated by integrin activation and hnRNP-K

Lisbeth S. Laursen, Colin W. Chan, Charles ffrench-Constant
Journal: Journal of Cell Biology
J Cell Biol (2011) 192 (5): 797–811.
https://doi.org/10.1083/jcb.201007014
Published: 28 February 2011
View article titled, Translation of myelin basic protein mRNA in oligodendrocytes is regulated by integrin activation and hnRNP-K
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Includes: Multimedia, Supplementary data
Journal Articles

Sulfonylurea Receptors Type 1 and 2A Randomly Assemble to Form Heteromeric KATP Channels of Mixed Subunit Composition

Kim W. Chan, Adam Wheeler, László Csanády
Journal: Journal of General Physiology
J Gen Physiol (2007) 131 (1): 43–58.
https://doi.org/10.1085/jgp.200709894
Published: 13 December 2007
View article titled, Sulfonylurea Receptors Type 1 and 2A Randomly Assemble to Form Heteromeric KATP Channels of Mixed Subunit Composition
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Includes: Supplementary data
Journal Articles

Preferential Phosphorylation of R-domain Serine 768 Dampens Activation of CFTR Channels by PKA

László Csanády, Donna Seto-Young, Kim W. Chan, Cristina Cenciarelli, Benjamin B. Angel, Jun Qin, Derek T. McLachlin, Andrew N. Krutchinsky, Brian T. Chait, Angus C. Nairn, David C. Gadsby
Journal: Journal of General Physiology
J Gen Physiol (2005) 125 (2): 171–186.
https://doi.org/10.1085/jgp.200409076
Published: 18 January 2005
View article titled, Preferential Phosphorylation of R-domain Serine 768 Dampens Activation of CFTR Channels by PKA
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Includes: Supplementary data
Journal Articles

Functional Roles of Nonconserved Structural Segments in CFTR's NH2-terminal Nucleotide Binding Domain

László Csanády, Kim W. Chan, Angus C. Nairn, David C. Gadsby
Journal: Journal of General Physiology
J Gen Physiol (2004) 125 (1): 43–55.
https://doi.org/10.1085/jgp.200409174
Published: 13 December 2004
View article titled, Functional Roles of Nonconserved Structural Segments in CFTR's NH2-terminal Nucleotide Binding Domain
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Journal Articles

Severed Channels Probe Regulation of Gating of Cystic Fibrosis Transmembrane Conductance Regulator by Its Cytoplasmic Domains

László Csanády, Kim W. Chan, Donna Seto-Young, David C. Kopsco, Angus C. Nairn, David C. Gadsby
Journal: Journal of General Physiology
J Gen Physiol (2000) 116 (3): 477–500.
https://doi.org/10.1085/jgp.116.3.477
Published: 28 August 2000
View article titled, Severed Channels Probe Regulation of Gating of Cystic Fibrosis Transmembrane Conductance Regulator by Its Cytoplasmic Domains
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Includes: Supplementary data
Journal Articles

Severed Molecules Functionally Define the Boundaries of the Cystic Fibrosis Transmembrane Conductance Regulator's Nh2-Terminal Nucleotide Binding Domain

Kim W. Chan, László Csanády, Donna Seto-Young, Angus C. Nairn, David C. Gadsby
Journal: Journal of General Physiology
J Gen Physiol (2000) 116 (2): 163–180.
https://doi.org/10.1085/jgp.116.2.163
Published: 17 July 2000
View article titled, Severed Molecules Functionally Define the Boundaries of the Cystic Fibrosis Transmembrane Conductance Regulator's Nh2-Terminal Nucleotide Binding Domain
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Journal Articles

Na+ activation of the muscarinic K+ channel by a G-protein-independent mechanism.

J L Sui, K W Chan, D E Logothetis
Journal: Journal of General Physiology
J Gen Physiol (1996) 108 (5): 381–391.
https://doi.org/10.1085/jgp.108.5.381
Published: 01 November 1996
View article titled, Na+ activation of the muscarinic K+ channel by a G-protein-independent mechanism.
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Journal Articles

Interleukin-1 beta-converting enzyme-like protease cleaves DNA-dependent protein kinase in cytotoxic T cell killing.

Q Song, S R Burrows, G Smith, S P Lees-Miller, S Kumar, D W Chan, J A Trapani, E Alnemri, G Litwack, H Lu, D J Moss, S Jackson, M F Lavin
Journal: Journal of Experimental Medicine
J Exp Med (1996) 184 (2): 619–626.
https://doi.org/10.1084/jem.184.2.619
Published: 01 August 1996
View article titled, Interleukin-1 beta-converting enzyme-like protease cleaves DNA-dependent protein kinase in cytotoxic T cell killing.
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Journal Articles

A recombinant inwardly rectifying potassium channel coupled to GTP-binding proteins.

K W Chan, M N Langan, J L Sui, J A Kozak, A Pabon, J A Ladias, D E Logothetis
Journal: Journal of General Physiology
J Gen Physiol (1996) 107 (3): 381–397.
https://doi.org/10.1085/jgp.107.3.381
Published: 01 March 1996
View article titled, A recombinant inwardly rectifying potassium channel coupled to GTP-binding proteins.
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Journal Articles

Protein tyrosine kinase p56-Lck regulates lymphocyte function-associated 1 adhesion molecule expression, granule exocytosis, and cytolytic effector function in a cloned T cell.

T Torigoe, J A Millan, K W Chan, R Taichman, A A Brian, J C Reed, R ] Tachman R [corrected to Taichman
Journal: Journal of Experimental Medicine
J Exp Med (1994) 180 (3): 1115–1127.
https://doi.org/10.1084/jem.180.3.1115
Published: 01 September 1994
View article titled, Protein tyrosine kinase p56-Lck regulates lymphocyte function-associated 1 adhesion molecule expression, granule exocytosis, and cytolytic effector function in a cloned T cell.
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Journal Articles

440-kD ankyrinB: structure of the major developmentally regulated domain and selective localization in unmyelinated axons.

W Chan, E Kordeli, V Bennett
Journal: Journal of Cell Biology
J Cell Biol (1993) 123 (6): 1463–1473.
https://doi.org/10.1083/jcb.123.6.1463
Published: 15 December 1993
View article titled, 440-kD ankyrinB: structure of the major developmentally regulated domain and selective localization in unmyelinated axons.
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