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Journal Articles

Ca2+ transients in melanocyte dendrites and dendritic spine-like structures evoked by cell-to-cell signaling

Rachel L. Belote, Sanford M. Simon
Journal: Journal of Cell Biology
J Cell Biol (2019) 219 (1): e201902014.
https://doi.org/10.1083/jcb.201902014
Published: 10 December 2019
View article titled, Ca2+ transients in melanocyte dendrites and dendritic spine-like structures evoked by cell-to-cell signaling
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Journal Articles

A coarse-grained computational model of the nuclear pore complex predicts Phe-Gly nucleoporin dynamics

Joan Pulupa, Manas Rachh, Michael D. Tomasini, Joshua S. Mincer, Sanford M. Simon
Journal: Journal of General Physiology
J Gen Physiol (2017) 149 (10): 951–966.
https://doi.org/10.1085/jgp.201711769
Published: 08 September 2017
View article titled, A coarse-grained computational model of the nuclear pore complex predicts Phe-Gly nucleoporin dynamics
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Includes: Supplementary data
Journal Articles

LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues

Keefe T. Chan, Sreeja B. Asokan, Samantha J. King, Tao Bo, Evan S. Dubose, Wenjin Liu, Matthew E. Berginski, Jeremy M. Simon, Ian J. Davis, Shawn M. Gomez, Norman E. Sharpless, James E. Bear
Journal: Journal of Cell Biology
J Cell Biol (2014) 207 (2): 299–315.
https://doi.org/10.1083/jcb.201404067
Published: 27 October 2014
View article titled, LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues
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Includes: Supplementary data
Journal Articles

Loss of Arp2/3 induces an NF-κB–dependent, nonautonomous effect on chemotactic signaling

Congying Wu, Elizabeth M. Haynes, Sreeja B. Asokan, Jeremy M. Simon, Norman E. Sharpless, Albert S. Baldwin, Ian J. Davis, Gary L. Johnson, James E. Bear
Journal: Journal of Cell Biology
J Cell Biol (2013) 203 (6): 907–916.
https://doi.org/10.1083/jcb.201306032
Published: 16 December 2013
View article titled, Loss of Arp2/3 induces an NF-κB–dependent, nonautonomous effect on chemotactic signaling
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Includes: Supplementary data
Journal Articles

Lack of the purinergic receptor P2X7 results in resistance to contact hypersensitivity

Felix C. Weber, Philipp R. Esser, Tobias Müller, Jayanthi Ganesan, Patrizia Pellegatti, Markus M. Simon, Robert Zeiser, Marco Idzko, Thilo Jakob, Stefan F. Martin
Journal: Journal of Experimental Medicine
J Exp Med (2010) 207 (12): 2609–2619.
https://doi.org/10.1084/jem.20092489
Published: 08 November 2010
View article titled, Lack of the purinergic receptor P2X7 results in resistance to contact hypersensitivity
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Includes: Supplementary data
Journal Articles

The mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in mice

Julian Pardo, Christin Urban, Eva M. Galvez, Paul G. Ekert, Uwe Müller, June Kwon-Chung, Mario Lobigs, Arno Müllbacher, Reinhard Wallich, Christoph Borner, Markus M. Simon
Journal: Journal of Cell Biology
J Cell Biol (2006) 174 (4): 509–519.
https://doi.org/10.1083/jcb.200604044
Published: 07 August 2006
View article titled, The mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in mice
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Journal Articles

Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis

Julián Pardo, Alberto Bosque, Reina Brehm, Reinhard Wallich, Javier Naval, Arno Müllbacher, Alberto Anel, Markus M. Simon
Journal: Journal of Cell Biology
J Cell Biol (2004) 167 (3): 457–468.
https://doi.org/10.1083/jcb.200406115
Published: 08 November 2004
View article titled, Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis
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Includes: Supplementary data
Journal Articles

Membrane proximal lysosomes are the major vesicles responsible for calcium-dependent exocytosis in nonsecretory cells

Jyoti K. Jaiswal, Norma W. Andrews, Sanford M. Simon
Journal: Journal of Cell Biology
J Cell Biol (2002) 159 (4): 625–635.
https://doi.org/10.1083/jcb.200208154
Published: 18 November 2002
View article titled, Membrane proximal lysosomes are the major vesicles responsible for calcium-dependent exocytosis in nonsecretory cells
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Journal Articles

Imaging Constitutive Exocytosis with Total Internal Reflection Fluorescence Microscopy

Jan Schmoranzer, Mark Goulian, Dan Axelrod, Sanford M. Simon
Journal: Journal of Cell Biology
J Cell Biol (2000) 149 (1): 23–32.
https://doi.org/10.1083/jcb.149.1.23
Published: 03 April 2000
View article titled, Imaging Constitutive Exocytosis with Total Internal Reflection Fluorescence Microscopy
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Journal Articles

In Situ Biochemical Demonstration That P-Glycoprotein Is a Drug Efflux Pump with Broad Specificity

Yu Chen, Sanford M. Simon
Journal: Journal of Cell Biology
J Cell Biol (2000) 148 (5): 863–870.
https://doi.org/10.1083/jcb.148.5.863
Published: 06 March 2000
View article titled, In Situ Biochemical Demonstration That P-Glycoprotein Is a Drug Efflux Pump with Broad Specificity
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Journal Articles

An Award for Cell Biology

Sanford M. Simon
Journal: Journal of Cell Biology
J Cell Biol (1999) 147 (5): 1–2.
https://doi.org/10.1083/jcb.147.5.1
Published: 29 November 1999
View article titled, An Award for Cell Biology
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Journal Articles

Defective Acidification in Human Breast Tumor Cells and Implications for Chemotherapy

Nihal Altan, Yu Chen, Melvin Schindler, Sanford M. Simon
Journal: Journal of Experimental Medicine
J Exp Med (1998) 187 (10): 1583–1598.
https://doi.org/10.1084/jem.187.10.1583
Published: 18 May 1998
View article titled, Defective Acidification in Human Breast Tumor Cells and Implications for Chemotherapy
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Journal Articles

In Vitro– and Ex Vivo–derived Cytolytic Leukocytes from Granzyme A × B Double Knockout Mice Are Defective in Granule-mediated Apoptosis but not Lysis of Target Cells

Markus M. Simon, Michael Hausmann, Thao Tran, Klaus Ebnet, Jürg Tschopp, Ron ThaHla, Arno Müllbacher
Journal: Journal of Experimental Medicine
J Exp Med (1997) 186 (10): 1781–1786.
https://doi.org/10.1084/jem.186.10.1781
Published: 17 November 1997
View article titled, In Vitro– and Ex Vivo–derived Cytolytic Leukocytes from Granzyme A × B Double Knockout Mice Are Defective in Granule-mediated Apoptosis but not Lysis of Target Cells
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Journal Articles

Microtubule dynamics at the G2/M transition: abrupt breakdown of cytoplasmic microtubules at nuclear envelope breakdown and implications for spindle morphogenesis.

Y Zhai, P J Kronebusch, P M Simon, G G Borisy
Journal: Journal of Cell Biology
J Cell Biol (1996) 135 (1): 201–214.
https://doi.org/10.1083/jcb.135.1.201
Published: 01 October 1996
View article titled, Microtubule dynamics at the G2/M transition: abrupt breakdown of cytoplasmic microtubules at nuclear envelope breakdown and implications for spindle morphogenesis.
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Journal Articles

Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin.

C Ruhrberg, M A Hajibagheri, M Simon, T P Dooley, F M Watt
Journal: Journal of Cell Biology
J Cell Biol (1996) 134 (3): 715–729.
https://doi.org/10.1083/jcb.134.3.715
Published: 01 August 1996
View article titled, Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin.
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Journal Articles

Transcription of granzyme A and B genes is differentially regulated during lymphoid ontogeny.

K Ebnet, C N Levelt, T T Tran, K Eichmann, M M Simon
Journal: Journal of Experimental Medicine
J Exp Med (1995) 181 (2): 755–763.
https://doi.org/10.1084/jem.181.2.755
Published: 01 February 1995
View article titled, Transcription of granzyme A and B genes is differentially regulated during lymphoid ontogeny.
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Journal Articles

The severe combined immunodeficiency (scid) mouse. A laboratory model for the analysis of Lyme arthritis and carditis.

U E Schaible, M D Kramer, C Museteanu, G Zimmer, H Mossmann, M M Simon
Journal: Journal of Experimental Medicine
J Exp Med (1989) 170 (4): 1427–1432.
https://doi.org/10.1084/jem.170.4.1427
Published: 01 October 1989
View article titled, The severe combined immunodeficiency (scid) mouse. A laboratory model for the analysis of Lyme arthritis and carditis.
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Journal Articles

Limiting dilution analysis of Epstein-Barr virus-induced immunoglobulin production by human B cells.

R Yarchoan, G Tosato, R M Blaese, R M Simon, D L Nelson
Journal: Journal of Experimental Medicine
J Exp Med (1983) 157 (1): 1–14.
https://doi.org/10.1084/jem.157.1.1
Published: 01 January 1983
View article titled, Limiting dilution analysis of Epstein-Barr virus-induced immunoglobulin production by human B cells.
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Journal Articles

Effector T lymphocytes in lymphocytic choriomeningitis virus-infected mice. Cytolytic activity of Lyt-23 spleen cells in vitro does not correlate with elimination of infectious virus from spleens.

M Varho, F Lehmann Grube, M M Simon
Journal: Journal of Experimental Medicine
J Exp Med (1981) 153 (4): 992–997.
https://doi.org/10.1084/jem.153.4.992
Published: 01 April 1981
View article titled, Effector T lymphocytes in lymphocytic choriomeningitis virus-infected mice. Cytolytic activity of Lyt-23 spleen cells in vitro does not correlate with elimination of infectious virus from spleens.
Open the PDF for Effector T lymphocytes in lymphocytic choriomeningitis virus-infected mice. Cytolytic activity of Lyt-23 spleen cells in vitro does not correlate with elimination of infectious virus from spleens. in another window
Journal Articles

Quantitative studies on T cell diversity. II. Determination of the frequencies and Lyt phenotypes of two types of precursor cells for alloreactive cytotoxic T cells in polyclonally and specifically activated splenic T cells.

J Goronzy, U Schaefer, K Eichmann, M M Simon
Journal: Journal of Experimental Medicine
J Exp Med (1981) 153 (4): 857–870.
https://doi.org/10.1084/jem.153.4.857
Published: 01 April 1981
View article titled, Quantitative studies on T cell diversity. II. Determination of the frequencies and Lyt phenotypes of two types of precursor cells for alloreactive cytotoxic T cells in polyclonally and specifically activated splenic T cells.
Open the PDF for Quantitative studies on T cell diversity. II. Determination of the frequencies and Lyt phenotypes of two types of precursor cells for alloreactive cytotoxic T cells in polyclonally and specifically activated splenic T cells. in another window