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Journal Articles

Dependence of myosin filament structure on intracellular calcium concentration in skeletal muscle

Marco Caremani, Luca Fusi, Massimo Reconditi, Gabriella Piazzesi, Theyencheri Narayanan, Malcolm Irving, Vincenzo Lombardi, Marco Linari, Elisabetta Brunello
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (12): e202313393.
https://doi.org/10.1085/jgp.202313393
Published: 27 September 2023
View article titled, Dependence of myosin filament structure on intracellular calcium concentration in skeletal muscle
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Journal Articles

The biophysical properties of TRIC-A and TRIC-B and their interactions with RyR2

Jianshu Hu, Elisa Venturi, Charalampos Sigalas, Takashi Murayama, Miyuki Nishi, Hiroshi Takeshima, Rebecca Sitsapesan
Journal: Journal of General Physiology
Series: Excitation–Contraction Coupling
J Gen Physiol (2023) 155 (11): e202113070.
https://doi.org/10.1085/jgp.202113070
Published: 26 September 2023
View article titled, The biophysical properties of TRIC-A and TRIC-B and their interactions with RyR2
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Includes: Supplementary data
Journal Articles

Mechanisms of dihydropyridine agonists and antagonists in view of cryo-EM structures of calcium and sodium channels

Denis B. Tikhonov, Boris S. Zhorov
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (11): e202313418.
https://doi.org/10.1085/jgp.202313418
Published: 20 September 2023
View article titled, Mechanisms of dihydropyridine agonists and antagonists in view of cryo-EM structures of calcium and sodium channels
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Journal Articles

Calcium binding and permeation in TRPV channels: Insights from molecular dynamics simulations

Chunhong Liu, Lingfeng Xue, Chen Song
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (12): e202213261.
https://doi.org/10.1085/jgp.202213261
Published: 20 September 2023
View article titled, Calcium binding and permeation in TRPV channels: Insights from molecular dynamics simulations
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Includes: Supplementary data
Journal Articles

Cardiomyocyte ryanodine receptor clusters expand and coalesce after application of isoproterenol

David R.L. Scriven, Anne Berit Johnsen, Parisa Asghari, Keng C. Chou, Edwin D.W. Moore
Journal: Journal of General Physiology
Series: Excitation–Contraction Coupling
J Gen Physiol (2023) 155 (11): e202213109.
https://doi.org/10.1085/jgp.202213109
Published: 20 September 2023
View article titled, Cardiomyocyte ryanodine receptor clusters expand and coalesce after application of isoproterenol
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Journal Articles

Disease-associated KCNMA1 variants decrease circadian clock robustness in channelopathy mouse models

Ria L. Dinsdale, Cooper E. Roache, Andrea L. Meredith
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (11): e202313357.
https://doi.org/10.1085/jgp.202313357
Published: 20 September 2023
View article titled, Disease-associated <em>KCNMA1</em> variants decrease circadian clock robustness in channelopathy mouse models
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Includes: Supplementary data
Journal Articles

Cooperative mechanisms underlie differences in myocardial contractile dynamics between large and small mammals

Jitandrakumar R. Patel, Kayla J.V. Park, Aidan S. Bradshaw, Tuan Phan, Daniel P. Fitzsimons
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (11): e202213315.
https://doi.org/10.1085/jgp.202213315
Published: 19 September 2023
View article titled, Cooperative mechanisms underlie differences in myocardial contractile dynamics between large and small mammals
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Includes: Supplementary data
Journal Articles

The fast block to polyspermy breaks with convention

Ben Short
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (10): e202313478.
https://doi.org/10.1085/jgp.202313478
Published: 13 September 2023
View article titled, The fast block to polyspermy breaks with convention
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Journal Articles

ANO1, CaV1.2, and IP3R form a localized unit of EC-coupling in mouse pulmonary arterial smooth muscle

Elizabeth J. Akin, Joydeep Aoun, Connor Jimenez, Katie Mayne, Julius Baeck, Michael D. Young, Brennan Sullivan, Kenton M. Sanders, Sean M. Ward, Simon Bulley, Jonathan H. Jaggar, Scott Earley, Iain A. Greenwood, Normand Leblanc
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (11): e202213217.
https://doi.org/10.1085/jgp.202213217
Published: 13 September 2023
View article titled, ANO1, Ca<sub>V</sub>1.2, and IP<sub>3</sub>R form a localized unit of EC-coupling in mouse pulmonary arterial smooth muscle
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Includes: Supplementary data
Journal Articles

Correction: Longitudinal diffusion barriers imposed by myofilaments and mitochondria in murine cardiac myocytes

Christine Deisl, Jay H. Chung, Donald W. Hilgemann
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (10): e20221332908212023c.
https://doi.org/10.1085/jgp.20221332908212023c
Published: 04 September 2023
View article titled, Correction: Longitudinal diffusion barriers imposed by myofilaments and mitochondria in murine cardiac myocytes
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Journal Articles

Myosin expression and contractile function are altered by replating stem cell–derived cardiomyocytes

Felix Osten, Natalie Weber, Meike Wendland, Tim Holler, Birgit Piep, Simon Kröhn, Jana Teske, Alea K. Bodenschatz, Santoshi Biswanath Devadas, Kaja S. Menge, Shambhabi Chatterjee, Kristin Schwanke, Maike Kosanke, Judith Montag, Thomas Thum, Robert Zweigerdt, Theresia Kraft, Bogdan Iorga, Joachim D. Meissner
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (11): e202313377.
https://doi.org/10.1085/jgp.202313377
Published: 01 September 2023
View article titled, Myosin expression and contractile function are altered by replating stem cell–derived cardiomyocytes
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Includes: Supplementary data
Journal Articles

The physical basis of osmosis

Gerald S. Manning, Alan R. Kay
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (10): e202313332.
https://doi.org/10.1085/jgp.202313332
Published: 25 August 2023
View article titled, The physical basis of osmosis
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Journal Articles

Mitochondrial morphology governs ATP production rate

Guadalupe C. Garcia, Kavya Gupta, Thomas M. Bartol, Terrence J. Sejnowski, Padmini Rangamani
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (9): e202213263.
https://doi.org/10.1085/jgp.202213263
Published: 24 August 2023
View article titled, Mitochondrial morphology governs ATP production rate
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Journal Articles

Correction: Urea and water are transported through different pathways in the red blood cell membrane

Jesper Brahm, Morten Hanefeld Dziegiel, Jonas Leifelt
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (9): e20221332208082023c.
https://doi.org/10.1085/jgp.20221332208082023c
Published: 22 August 2023
View article titled, Correction: Urea and water are transported through different pathways in the red blood cell membrane
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Journal Articles

Kv12 channels flick the switch

Ben Short
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (9): e202313459.
https://doi.org/10.1085/jgp.202313459
Published: 16 August 2023
View article titled, Kv12 channels flick the switch
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Journal Articles

Epilepsy-associated SCN2A (NaV1.2) variants exhibit diverse and complex functional properties

Christopher H. Thompson, Franck Potet, Tatiana V. Abramova, Jean-Marc DeKeyser, Nora F. Ghabra, Carlos G. Vanoye, John J. Millichap, Alfred L. George, Jr
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (10): e202313375.
https://doi.org/10.1085/jgp.202313375
Published: 14 August 2023
View article titled, Epilepsy-associated <em>SCN2A</em> (Na<sub>V</sub>1.2) variants exhibit diverse and complex functional properties
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Includes: Supplementary data
Journal Articles

TMEM16A activation for the fast block to polyspermy in the African clawed frog does not require conventional activation of egg PLCs

Kayla M. Komondor, Rachel E. Bainbridge, Katherine G. Sharp, Anuradha R. Iyer, Joel C. Rosenbaum, Anne E. Carlson
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (10): e202213258.
https://doi.org/10.1085/jgp.202213258
Published: 10 August 2023
View article titled, TMEM16A activation for the fast block to polyspermy in the African clawed frog does not require conventional activation of egg PLCs
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Includes: Supplementary data
Journal Articles

Longitudinal diffusion barriers imposed by myofilaments and mitochondria in murine cardiac myocytes

Christine Deisl, Jay H. Chung, Donald W. Hilgemann
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (10): e202213329.
https://doi.org/10.1085/jgp.202213329
Published: 09 August 2023
View article titled, Longitudinal diffusion barriers imposed by myofilaments and mitochondria in murine cardiac myocytes
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Includes: Supplementary data
Journal Articles

Cold and warmth intensify pain-linked sodium channel gating effects and persistent currents

In Special Collection:
Physiology of Pain Detection and Processing Collection 2023
Sophia Kriegeskorte, Raya Bott, Martin Hampl, Alon Korngreen, Ralf Hausmann, Angelika Lampert
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (9): e202213312.
https://doi.org/10.1085/jgp.202213312
Published: 02 August 2023
View article titled, Cold and warmth intensify pain-linked sodium channel gating effects and persistent currents
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Includes: Supplementary data
Journal Articles

Urea transport in human red blood cells: Donor variation compared to chloride, glucose, and water transport

Jonas Leifelt, Morten Hanefeld Dziegiel, Jesper Brahm
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (10): e202213321.
https://doi.org/10.1085/jgp.202213321
Published: 02 August 2023
View article titled, Urea transport in human red blood cells: Donor variation compared to chloride, glucose, and water transport
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