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Journal Articles

How does mitochondrial Ca2+ change during ischemia and reperfusion? Implications for activation of the permeability transition pore

Elizabeth Murphy, David A. Eisner
Journal: Journal of General Physiology
J Gen Physiol (2024) 157 (1): e202313520.
https://doi.org/10.1085/jgp.202313520
Published: 19 December 2024
View article titled, How does mitochondrial Ca<sup>2+</sup> change during ischemia and reperfusion? Implications for activation of the permeability transition pore
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Journal Articles

Ion channels of cold transduction and transmission

In Special Collection:
Molecular Insights into Membrane Protein Function
Cheyanne M. Lewis, Theanne N. Griffith
Journal: Journal of General Physiology
Series: Pain Focus
J Gen Physiol (2024) 156 (10): e202313529.
https://doi.org/10.1085/jgp.202313529
Published: 25 July 2024
View article titled, Ion channels of cold transduction and transmission
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Journal Articles

Fifty years of gating currents and channel gating

Luigi Catacuzzeno, Franco Conti, Fabio Franciolini
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (8): e202313380.
https://doi.org/10.1085/jgp.202313380
Published: 06 July 2023
View article titled, Fifty years of gating currents and channel gating
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Journal Articles

The role of Zn2+ in shaping intracellular Ca2+ dynamics in the heart

Amy M. Dorward, Alan J. Stewart, Samantha J. Pitt
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (7): e202213206.
https://doi.org/10.1085/jgp.202213206
Published: 16 June 2023
View article titled, The role of Zn<sup>2+</sup> in shaping intracellular Ca<sup>2+</sup> dynamics in the heart
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Journal Articles

Eccentric contraction-induced strength loss in dystrophin-deficient muscle: Preparations, protocols, and mechanisms

Leonit Kiriaev, Cory W. Baumann, Angus Lindsay
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (2): e202213208.
https://doi.org/10.1085/jgp.202213208
Published: 18 January 2023
View article titled, Eccentric contraction-induced strength loss in dystrophin-deficient muscle: Preparations, protocols, and mechanisms
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Journal Articles

Role of ryanodine receptor 2 and FK506-binding protein 12.6 dissociation in pulmonary hypertension

Yong-Xiao Wang, Jorge Reyes-García, Annarita Di Mise, Yun-Min Zheng
Journal: Journal of General Physiology
Series: Excitation–Contraction Coupling
J Gen Physiol (2023) 155 (3): e202213100.
https://doi.org/10.1085/jgp.202213100
Published: 10 January 2023
View article titled, Role of ryanodine receptor 2 and FK506-binding protein 12.6 dissociation in pulmonary hypertension
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Journal Articles

Ion channel regulation of gut immunity

Jing Feng, Zili Xie, Hongzhen Hu
Journal: Journal of General Physiology
Series: Channels and Transporters in Immunity
J Gen Physiol (2022) 155 (2): e202113042.
https://doi.org/10.1085/jgp.202113042
Published: 02 December 2022
View article titled, Ion channel regulation of gut immunity
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Journal Articles

Mechanistic insights on KATP channel regulation from cryo-EM structures

Camden M. Driggers, Show-Ling Shyng
Journal: Journal of General Physiology
J Gen Physiol (2022) 155 (1): e202113046.
https://doi.org/10.1085/jgp.202113046
Published: 28 November 2022
View article titled, Mechanistic insights on K<sub>ATP</sub> channel regulation from cryo-EM structures
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Journal Articles

Mutations in proteins involved in E-C coupling and SOCE and congenital myopathies

Daniela Rossi, Maria Rosaria Catallo, Enrico Pierantozzi, Vincenzo Sorrentino
Journal: Journal of General Physiology
Series: Excitation–Contraction Coupling
J Gen Physiol (2022) 154 (9): e202213115.
https://doi.org/10.1085/jgp.202213115
Published: 18 August 2022
View article titled, Mutations in proteins involved in E-C coupling and SOCE and congenital myopathies
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Journal Articles

A controversial issue: Can mitochondria modulate cytosolic calcium and contraction of skeletal muscle fibers?

Carlo Reggiani, Lorenzo Marcucci
Journal: Journal of General Physiology
Series: Excitation–Contraction Coupling
J Gen Physiol (2022) 154 (9): e202213167.
https://doi.org/10.1085/jgp.202213167
Published: 18 July 2022
View article titled, A controversial issue: Can mitochondria modulate cytosolic calcium and contraction of skeletal muscle fibers?
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Journal Articles

Physics of mechanotransduction by Piezo ion channels

Michael Young, Amanda H. Lewis, Jörg Grandl
Journal: Journal of General Physiology
Series: Mechanotransduction by Membrane Proteins
J Gen Physiol (2022) 154 (7): e202113044.
https://doi.org/10.1085/jgp.202113044
Published: 20 May 2022
View article titled, Physics of mechanotransduction by Piezo ion channels
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Journal Articles

Biophysical physiology of phosphoinositide rapid dynamics and regulation in living cells

Jill B. Jensen, Bjoern H. Falkenburger, Eamonn J. Dickson, Lizbeth de la Cruz, Gucan Dai, Jongyun Myeong, Seung-Ryoung Jung, Martin Kruse, Oscar Vivas, Byung-Chang Suh, Bertil Hille
Journal: Journal of General Physiology
J Gen Physiol (2022) 154 (6): e202113074.
https://doi.org/10.1085/jgp.202113074
Published: 18 May 2022
View article titled, Biophysical physiology of phosphoinositide rapid dynamics and regulation in living cells
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Journal Articles

Biological noise is a key determinant of the reproducibility and adaptability of cardiac pacemaking and EC coupling

Laura Guarina, Ariana Neelufar Moghbel, Mohammad S. Pourhosseinzadeh, Robert H. Cudmore, Daisuke Sato, Colleen E. Clancy, Luis Fernando Santana
Journal: Journal of General Physiology
Series: Excitation–Contraction Coupling
J Gen Physiol (2022) 154 (9): e202012613.
https://doi.org/10.1085/jgp.202012613
Published: 28 April 2022
View article titled, Biological noise is a key determinant of the reproducibility and adaptability of cardiac pacemaking and EC coupling
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Journal Articles

Functional and structural differences between skinned and intact muscle preparations

Alex Lewalle, Kenneth S. Campbell, Stuart G. Campbell, Gregory N. Milburn, Steven A. Niederer
Journal: Journal of General Physiology
J Gen Physiol (2022) 154 (2): e202112990.
https://doi.org/10.1085/jgp.202112990
Published: 19 January 2022
View article titled, Functional and structural differences between skinned and intact muscle preparations
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Journal Articles

The molecular evolution of function in the CFTR chloride channel

Daniel T. Infield, Kerry M. Strickland, Amit Gaggar, Nael A. McCarty
Journal: Journal of General Physiology
J Gen Physiol (2021) 153 (12): e202012625.
https://doi.org/10.1085/jgp.202012625
Published: 14 October 2021
View article titled, The molecular evolution of function in the CFTR chloride channel
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Journal Articles

Novel insights into sarcomere regulatory systems control of cardiac thin filament activation

Christopher Solís, R. John Solaro
Journal: Journal of General Physiology
J Gen Physiol (2021) 153 (7): e202012777.
https://doi.org/10.1085/jgp.202012777
Published: 19 March 2021
View article titled, Novel insights into sarcomere regulatory systems control of cardiac thin filament activation
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Journal Articles

The role of molecular diffusion within dendritic spines in synaptic function

In Special Collection:
Neuroscience Collection 2021
Kazuki Obashi, Justin W. Taraska, Shigeo Okabe
Journal: Journal of General Physiology
J Gen Physiol (2021) 153 (4): e202012814.
https://doi.org/10.1085/jgp.202012814
Published: 15 March 2021
View article titled, The role of molecular diffusion within dendritic spines in synaptic function
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Journal Articles

FXYD proteins and sodium pump regulatory mechanisms

John Q. Yap, Jaroslava Seflova, Ryan Sweazey, Pablo Artigas, Seth L. Robia
Journal: Journal of General Physiology
J Gen Physiol (2021) 153 (4): e202012633.
https://doi.org/10.1085/jgp.202012633
Published: 10 March 2021
View article titled, FXYD proteins and sodium pump regulatory mechanisms
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Journal Articles

Filament evanescence of myosin II and smooth muscle function

Lu Wang, Pasquale Chitano, Chun Y. Seow
Journal: Journal of General Physiology
J Gen Physiol (2021) 153 (3): e202012781.
https://doi.org/10.1085/jgp.202012781
Published: 19 February 2021
View article titled, Filament evanescence of myosin II and smooth muscle function
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Journal Articles

Complexity in genetic cardiomyopathies and new approaches for mechanism-based precision medicine

In Special Collection:
Cardiac Physiology 2021
Michael J. Greenberg, Jil C. Tardiff
Journal: Journal of General Physiology
J Gen Physiol (2021) 153 (3): e202012662.
https://doi.org/10.1085/jgp.202012662
Published: 29 January 2021
View article titled, Complexity in genetic cardiomyopathies and new approaches for mechanism-based precision medicine
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