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Journal Articles

Obscurin deficiency leads to compensated dilated cardiomyopathy and increased arrhythmias

Josè Manuel Pioner, Enrico Pierantozzi, Raffaele Coppini, Egidio Maria Rubino, Valentina Biasci, Giulia Vitale, Annunziatina Laurino, Lorenzo Santini, Marina Scardigli, Davide Randazzo, Camilla Olianti, Matteo Serano, Daniela Rossi, Chiara Tesi, Elisabetta Cerbai, Stephan Lange, Carlo Reggiani, Leonardo Sacconi, Corrado Poggesi, Cecilia Ferrantini, Vincenzo Sorrentino
Journal: Journal of General Physiology
Series: Contractile Function
J Gen Physiol (2025) 157 (4): e202413696.
https://doi.org/10.1085/jgp.202413696
Published: 14 May 2025
View articletitled, Obscurin deficiency leads to compensated dilated cardiomyopathy and increased arrhythmias
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Includes: Supplementary data
Journal Articles

Glycerol storage increases passive stiffness of muscle fibers through effects on titin extensibility

Seong-Won Han, Justin Kolb, Gerrie P. Farman, Jochen Gohlke, Henk L. Granzier
Journal: Journal of General Physiology
Series: Contractile Function
J Gen Physiol (2025) 157 (4): e202413729.
https://doi.org/10.1085/jgp.202413729
Published: 09 May 2025
View articletitled, Glycerol storage increases passive stiffness of muscle fibers through effects on titin extensibility
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Includes: Supplementary data
Journal Articles

Prediction and biological significance of small changes in binding of leiomodin to tropomyosin

Eduardo Sánchez Díaz, Brayan Osegueda, Svetlana Minakhina, Nickolas Starks, Stefanie Novak, Dmitri Tolkatchev, Carol C. Gregorio, Alla S. Kostyukova, Garry E. Smith, Jr
Journal: Journal of General Physiology
Series: Contractile Function
J Gen Physiol (2025) 157 (4): e202413641.
https://doi.org/10.1085/jgp.202413641
Published: 24 April 2025
View articletitled, Prediction and biological significance of small changes in binding of leiomodin to tropomyosin
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Includes: Supplementary data
Journal Articles

Myosin binding protein-C modulates loaded sarcomere shortening in rodent permeabilized cardiac myocytes

Kerry S. McDonald, Theodore J. Kalogeris, Adam B. Veteto, Daniel J. Davis, Laurin M. Hanft
Journal: Journal of General Physiology
Series: Contractile Function
J Gen Physiol (2025) 157 (3): e202413678.
https://doi.org/10.1085/jgp.202413678
Published: 24 March 2025
View articletitled, Myosin binding protein-C modulates loaded sarcomere shortening in rodent permeabilized cardiac myocytes
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Journal Articles

Marfan syndrome cardiomyocytes show excess of titin isoform N2BA and extended sarcomeric M-band

Dalma Kellermayer, Cristina M. Șulea, Hedvig Tordai, Kálmán Benke, Miklós Pólos, Bence Ágg, Roland Stengl, Máté Csonka, Tamás Radovits, Béla Merkely, Zoltán Szabolcs, Miklós Kellermayer, Balázs Kiss
Journal: Journal of General Physiology
Series: Contractile Function
J Gen Physiol (2025) 157 (3): e202413690.
https://doi.org/10.1085/jgp.202413690
Published: 10 March 2025
View articletitled, Marfan syndrome cardiomyocytes show excess of titin isoform N2BA and extended sarcomeric M-band
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Includes: Supplementary data
Journal Articles

Structural and functional insights into α-actinin isoforms and their implications in cardiovascular disease

Maya Noureddine, Halina Mikolajek, Neil V. Morgan, Chris Denning, Siobhan Loughna, Katja Gehmlich, Fiyaz Mohammed
Journal: Journal of General Physiology
Series: Contractile Function
J Gen Physiol (2025) 157 (2): e202413684.
https://doi.org/10.1085/jgp.202413684
Published: 07 February 2025
View articletitled, Structural and functional insights into α-actinin isoforms and their implications in cardiovascular disease
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Includes: Supplementary data
Journal Articles

Functional role of myosin-binding protein H in thick filaments of developing vertebrate fast-twitch skeletal muscle

Andrew F. Mead, Neil B. Wood, Shane R. Nelson, Bradley M. Palmer, Lin Yang, Samantha Beck Previs, Angela Ploysangngam, Guy G. Kennedy, Jennifer F. McAdow, Sarah M. Tremble, Marcus A. Zimmermann, Marilyn J. Cipolla, Alicia M. Ebert, Aaron N. Johnson, Christina A. Gurnett, Michael J. Previs, David M. Warshaw
Journal: Journal of General Physiology
Series: Contractile Function
J Gen Physiol (2024) 156 (12): e202413604.
https://doi.org/10.1085/jgp.202413604
Published: 07 October 2024
View articletitled, Functional role of myosin-binding protein H in thick filaments of developing vertebrate fast-twitch skeletal muscle
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Includes: Supplementary data
Journal Articles

Calcium has a direct effect on thick filament activation in porcine myocardium

Saffie Mohran, Timothy S. McMillen, Christian Mandrycky, An-Yue Tu, Kristina B. Kooiker, Wenjing Qian, Stephanie Neys, Brayan Osegueda, Farid Moussavi-Harami, Thomas C. Irving, Michael Regnier, Weikang Ma
Journal: Journal of General Physiology
J Gen Physiol (2024) 156 (11): e202413545.
https://doi.org/10.1085/jgp.202413545
Published: 20 September 2024
View articletitled, Calcium has a direct effect on thick filament activation in porcine myocardium
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