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Journal Articles

Cysteine accessibility probes timing and extent of NBD separation along the dimer interface in gating CFTR channels

Luiz A. Poletto Chaves, David C. Gadsby

J Gen Physiol (2015) 145 (4): 261–283.

https://doi.org/10.1085/jgp.201411347

Published: 30 March 2015

View article titled, Cysteine accessibility probes timing and extent of NBD separation along the dimer interface in gating CFTR channels

Includes: Supplementary data

Journal Articles

Route, mechanism, and implications of proton import during Na⁺/K⁺ exchange by native Na⁺/K⁺-ATPase pumps

Natascia Vedovato, David C. Gadsby

J Gen Physiol (2014) 143 (4): 449–464.

https://doi.org/10.1085/jgp.201311148

Published: 31 March 2014

View article titled, Route, mechanism, and implications of proton import during Na+/K+ exchange by native Na+/K+-ATPase pumps

Includes: Supplementary data

Journal Articles

The two C-terminal tyrosines stabilize occluded Na/K pump conformations containing Na or K ions

Natascia Vedovato, David C. Gadsby

J Gen Physiol (2010) 136 (1): 63–82.

https://doi.org/10.1085/jgp.201010407

Published: 14 June 2010

View article titled, The two C-terminal tyrosines stabilize occluded Na/K pump conformations containing Na or K ions

Includes: Supplementary data

Journal Articles

Sodium Flux Ratio in Na/K Pump-Channels Opened by Palytoxin

R.F. Rakowski, Pablo Artigas, Francisco Palma, Miguel Holmgren, Paul De Weer, David C. Gadsby

J Gen Physiol (2007) 130 (1): 41–54.

https://doi.org/10.1085/jgp.200709770

Published: 11 June 2007

View article titled, Sodium Flux Ratio in Na/K Pump-Channels Opened by Palytoxin

Includes: Supplementary data

Journal Articles

Thermodynamics of CFTR Channel Gating: A Spreading Conformational Change Initiates an Irreversible Gating Cycle

László Csanády, Angus C. Nairn, David C. Gadsby

J Gen Physiol (2006) 128 (5): 523–533.

https://doi.org/10.1085/jgp.200609558

Published: 16 October 2006

View article titled, Thermodynamics of CFTR Channel Gating: A Spreading Conformational Change Initiates an Irreversible Gating Cycle

Includes: Supplementary data

Journal Articles

Preferential Phosphorylation of R-domain Serine 768 Dampens Activation of CFTR Channels by PKA

László Csanády, Donna Seto-Young, Kim W. Chan, Cristina Cenciarelli, Benjamin B. Angel, Jun Qin, Derek T. McLachlin, Andrew N. Krutchinsky, Brian T. Chait, Angus C. Nairn, David C. Gadsby

J Gen Physiol (2005) 125 (2): 171–186.

https://doi.org/10.1085/jgp.200409076

Published: 18 January 2005

View article titled, Preferential Phosphorylation of R-domain Serine 768 Dampens Activation of CFTR Channels by PKA

Includes: Supplementary data

Journal Articles

Functional Roles of Nonconserved Structural Segments in CFTR's NH₂-terminal Nucleotide Binding Domain

László Csanády, Kim W. Chan, Angus C. Nairn, David C. Gadsby

J Gen Physiol (2004) 125 (1): 43–55.

https://doi.org/10.1085/jgp.200409174

Published: 13 December 2004

View article titled, Functional Roles of Nonconserved Structural Segments in CFTR's NH2-terminal Nucleotide Binding Domain

Journal Articles

Large Diameter of Palytoxin-induced Na/K Pump Channels and Modulation of Palytoxin Interaction by Na/K Pump Ligands

Pablo Artigas, David C. Gadsby

J Gen Physiol (2004) 123 (4): 357–376.

https://doi.org/10.1085/jgp.200308964

Published: 15 March 2004

View article titled, Large Diameter of Palytoxin-induced Na/K Pump Channels and Modulation of Palytoxin Interaction by Na/K Pump Ligands

Journal Articles

Prolonged Nonhydrolytic Interaction of Nucleotide with CFTR's NH₂-terminal Nucleotide Binding Domain and its Role in Channel Gating

Claudia Basso, Paola Vergani, Angus C. Nairn, David C. Gadsby

J Gen Physiol (2003) 122 (3): 333–348.

https://doi.org/10.1085/jgp.200308798

Published: 25 August 2003

View article titled, Prolonged Nonhydrolytic Interaction of Nucleotide with CFTR's NH2-terminal Nucleotide Binding Domain and its Role in Channel Gating

Journal Articles

Paul F. Cranefield, M.D., Ph.D. April 28, 1925 to May 31, 2003

Olaf S. Andersen, David C. Gadsby, Michael J. Held

J Gen Physiol (2003) 122 (1): 1–2.

https://doi.org/10.1085/jgp.200308887

Published: 30 June 2003

View article titled, Paul F. Cranefield, M.D., Ph.D. April 28, 1925 to May 31, 2003

Journal Articles

On the Mechanism of MgATP-dependent Gating of CFTR Cl⁻ Channels

Paola Vergani, Angus C. Nairn, David C. Gadsby

J Gen Physiol (2002) 121 (1): 17–36.

https://doi.org/10.1085/jgp.20028673

Published: 16 December 2002

View article titled, On the Mechanism of MgATP-dependent Gating of CFTR Cl− Channels

Journal Articles

Distinct Mg²⁺-dependent Steps Rate Limit Opening and Closing of a Single CFTR Cl⁻ Channel

Athanasios G. Dousmanis, Angus C. Nairn, David C. Gadsby

J Gen Physiol (2002) 119 (6): 545–559.

https://doi.org/10.1085/jgp.20028594

Published: 28 May 2002

View article titled, Distinct Mg2+-dependent Steps Rate Limit Opening and Closing of a Single CFTR Cl− Channel

Journal Articles

Single Ion Occupancy and Steady-state Gating of Na Channels in Squid Giant Axon

Robert F. Rakowski, David C. Gadsby, Paul De Weer

J Gen Physiol (2002) 119 (3): 235–250.

https://doi.org/10.1085/jgp.20028500

Published: 22 February 2002

View article titled, Single Ion Occupancy and Steady-state Gating of Na Channels in Squid Giant Axon

Journal Articles

Voltage Dependence of the Apparent Affinity for External Na⁺ of the Backward-Running Sodium Pump

Paul De Weer, David C. Gadsby, R.F. Rakowski

J Gen Physiol (2001) 117 (4): 315–328.

https://doi.org/10.1085/jgp.117.4.315

Published: 12 March 2001

View article titled, Voltage Dependence of the Apparent Affinity for External Na+ of the Backward-Running Sodium Pump

Journal Articles

Severed Channels Probe Regulation of Gating of Cystic Fibrosis Transmembrane Conductance Regulator by Its Cytoplasmic Domains

László Csanády, Kim W. Chan, Donna Seto-Young, David C. Kopsco, Angus C. Nairn, David C. Gadsby

J Gen Physiol (2000) 116 (3): 477–500.

https://doi.org/10.1085/jgp.116.3.477

Published: 28 August 2000

View article titled, Severed Channels Probe Regulation of Gating of Cystic Fibrosis Transmembrane Conductance Regulator by Its Cytoplasmic Domains

Includes: Supplementary data

Journal Articles

Severed Molecules Functionally Define the Boundaries of the Cystic Fibrosis Transmembrane Conductance Regulator's Nh₂-Terminal Nucleotide Binding Domain

Kim W. Chan, László Csanády, Donna Seto-Young, Angus C. Nairn, David C. Gadsby

J Gen Physiol (2000) 116 (2): 163–180.

https://doi.org/10.1085/jgp.116.2.163

Published: 17 July 2000

View article titled, Severed Molecules Functionally Define the Boundaries of the Cystic Fibrosis Transmembrane Conductance Regulator's Nh2-Terminal Nucleotide Binding Domain

Journal Articles

The 53rd Annual Meeting and Symposium of the Society of General Physiologists New Optical Methods in Cell Physiology: (Organized by Brian M. Salzberg and Jack H. Kaplan)

David C. Gadsby

J Gen Physiol (2000) 115 (2): 223–226.

https://doi.org/10.1085/jgp.115.2.223

Published: 17 February 2000

View article titled, The 53rd Annual Meeting and Symposium of the Society of General Physiologists New Optical Methods in Cell Physiology: <subtitle>(Organized by Brian M. Salzberg and Jack H. Kaplan)</subtitle>

Journal Articles

Cftr Channel Gating : Incremental Progress in Irreversible Steps

László Csanády, David C. Gadsby

J Gen Physiol (1999) 114 (1): 49–54.

https://doi.org/10.1085/jgp.114.1.49

Published: 01 July 1999

View article titled, Cftr Channel Gating : <subtitle>Incremental Progress in Irreversible Steps </subtitle>

NARROW

Cysteine accessibility probes timing and extent of NBD separation along the dimer interface in gating CFTR channels

Route, mechanism, and implications of proton import during Na⁺/K⁺ exchange by native Na⁺/K⁺-ATPase pumps

The two C-terminal tyrosines stabilize occluded Na/K pump conformations containing Na or K ions

Sodium Flux Ratio in Na/K Pump-Channels Opened by Palytoxin

Thermodynamics of CFTR Channel Gating: A Spreading Conformational Change Initiates an Irreversible Gating Cycle

Preferential Phosphorylation of R-domain Serine 768 Dampens Activation of CFTR Channels by PKA

Functional Roles of Nonconserved Structural Segments in CFTR's NH₂-terminal Nucleotide Binding Domain

Large Diameter of Palytoxin-induced Na/K Pump Channels and Modulation of Palytoxin Interaction by Na/K Pump Ligands

Prolonged Nonhydrolytic Interaction of Nucleotide with CFTR's NH₂-terminal Nucleotide Binding Domain and its Role in Channel Gating

Paul F. Cranefield, M.D., Ph.D. April 28, 1925 to May 31, 2003

On the Mechanism of MgATP-dependent Gating of CFTR Cl⁻ Channels

Distinct Mg²⁺-dependent Steps Rate Limit Opening and Closing of a Single CFTR Cl⁻ Channel

Single Ion Occupancy and Steady-state Gating of Na Channels in Squid Giant Axon

Voltage Dependence of the Apparent Affinity for External Na⁺ of the Backward-Running Sodium Pump

Severed Channels Probe Regulation of Gating of Cystic Fibrosis Transmembrane Conductance Regulator by Its Cytoplasmic Domains

Severed Molecules Functionally Define the Boundaries of the Cystic Fibrosis Transmembrane Conductance Regulator's Nh₂-Terminal Nucleotide Binding Domain

The 53rd Annual Meeting and Symposium of the Society of General Physiologists New Optical Methods in Cell Physiology: (Organized by Brian M. Salzberg and Jack H. Kaplan)

Cftr Channel Gating : Incremental Progress in Irreversible Steps

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