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Journal Articles

Sensory neuron sodium channels as pain targets; from cocaine to Journavx (VX-548, suzetrigine)

John N. Wood, Nieng Yan, Jian Huang, Jing Zhao, Armen Akopian, James J. Cox, C. Geoffrey Woods, Mohammed A. Nassar

J Gen Physiol (2025) 157 (4): e202513778.

https://doi.org/10.1085/jgp.202513778

Published: 28 April 2025

View articletitled, Sensory neuron sodium channels as pain targets; from cocaine to Journavx (VX-548, suzetrigine)

Journal Articles

A realistic look at rod synapses

Ben Short

J Gen Physiol (2025) 157 (3): e202513804.

https://doi.org/10.1085/jgp.202513804

Published: 16 April 2025

View articletitled, A realistic look at rod synapses

Journal Articles

How the Blind Watchmaker messed around with potassium channels

Lawrence Salkoff

J Gen Physiol (2025) 157 (3): e202513783.

https://doi.org/10.1085/jgp.202513783

Published: 19 March 2025

View articletitled, How the Blind Watchmaker messed around with potassium channels

Journal Articles

A complete set of rate constants for a transporter’s catalytic cycle

Michael L. Jennings

J Gen Physiol (2025) 157 (3): e202513766.

https://doi.org/10.1085/jgp.202513766

Published: 21 February 2025

View articletitled, A complete set of rate constants for a transporter’s catalytic cycle

Journal Articles

FAT3 provides a flicker of light

Ben Short

J Gen Physiol (2025) 157 (2): e202513772.

https://doi.org/10.1085/jgp.202513772

Published: 11 February 2025

View articletitled, FAT3 provides a flicker of light

Journal Articles

Structural and functional insights into α-actinin isoforms and their implications in cardiovascular disease

Maya Noureddine, Halina Mikolajek, Neil V. Morgan, Chris Denning, Siobhan Loughna, Katja Gehmlich, Fiyaz Mohammed

J Gen Physiol (2025) 157 (2): e202413684.

https://doi.org/10.1085/jgp.202413684

Published: 07 February 2025

View articletitled, Structural and functional insights into α-actinin isoforms and their implications in cardiovascular disease

Includes: Supplementary data

Journal Articles

PANX1 hexamers work but cells prefer heptamers

Andrew L. Harris

J Gen Physiol (2025) 157 (2): e202413727.

https://doi.org/10.1085/jgp.202413727

Published: 05 February 2025

View articletitled, PANX1 hexamers work but cells prefer heptamers

Journal Articles

JGP in 2025

David Eisner

J Gen Physiol (2025) 157 (2): e202513758.

https://doi.org/10.1085/jgp.202513758

Published: 03 February 2025

View articletitled, JGP in 2025

Journal Articles

Modeling cardiac contractile cooperativity across species

Matthew Carter Childers

J Gen Physiol (2025) 157 (2): e202413722.

https://doi.org/10.1085/jgp.202413722

Published: 31 January 2025

View articletitled, Modeling cardiac contractile cooperativity across species

Journal Articles

Inactivation of Ca_V1 and Ca_V2 channels

Worawan B. Limpitikul, Ivy E. Dick

J Gen Physiol (2025) 157 (2): e202313531.

https://doi.org/10.1085/jgp.202313531

Published: 30 January 2025

View articletitled, Inactivation of CaV1 and CaV2 channels

Journal Articles

Understanding the role of mutations in voltage-gated sodium ion channels for cardiovascular disorders

Christian Jorgensen

J Gen Physiol (2025) 157 (2): e202413744.

https://doi.org/10.1085/jgp.202413744

Published: 23 January 2025

View articletitled, Understanding the role of mutations in voltage-gated sodium ion channels for cardiovascular disorders

Journal Articles

How could simulations elucidate Na_v1.5 channel blockers mechanism?

Tanadet Pipatpolkai

J Gen Physiol (2025) 157 (2): e202413730.

https://doi.org/10.1085/jgp.202413730

Published: 07 January 2025

View articletitled, How could simulations elucidate Nav1.5 channel blockers mechanism?

Journal Articles

How does mitochondrial Ca²⁺ change during ischemia and reperfusion? Implications for activation of the permeability transition pore

Elizabeth Murphy, David A. Eisner

J Gen Physiol (2024) 157 (1): e202313520.

https://doi.org/10.1085/jgp.202313520

Published: 19 December 2024

View articletitled, How does mitochondrial Ca2+ change during ischemia and reperfusion? Implications for activation of the permeability transition pore

Journal Articles

A misstep in the multistep process of fast inactivation

Ben Short

J Gen Physiol (2024) 157 (1): e202413735.

https://doi.org/10.1085/jgp.202413735

Published: 17 December 2024

View articletitled, A misstep in the multistep process of fast inactivation

Journal Articles

Time-dependent effect of FKBP12 loss in the development of dilated cardiomyopathy

Joan A. Chan, Michelle L. Munro

J Gen Physiol (2024) 157 (1): e202413673.

https://doi.org/10.1085/jgp.202413673

Published: 12 December 2024

View articletitled, Time-dependent effect of FKBP12 loss in the development of dilated cardiomyopathy

Journal Articles

A new stress test for ryanodine receptors

Ben Short

J Gen Physiol (2024) 156 (12): e202413716.

https://doi.org/10.1085/jgp.202413716

Published: 19 November 2024

View articletitled, A new stress test for ryanodine receptors

Journal Articles

Myosin-binding protein-H: Not just filler

David Y. Barefield

J Gen Physiol (2024) 156 (12): e202413622.

https://doi.org/10.1085/jgp.202413622

Published: 01 November 2024

View articletitled, Myosin-binding protein-H: Not just filler

Journal Articles

What happened to the pursuit of truth?

Eve Marder

J Gen Physiol (2024) 156 (11): e202413672.

https://doi.org/10.1085/jgp.202413672

Published: 23 October 2024

View articletitled, What happened to the pursuit of truth?

Journal Articles

Connecting the dots on connexin function

Ben Short

J Gen Physiol (2024) 156 (11): e202413675.

https://doi.org/10.1085/jgp.202413675

Published: 14 October 2024

View articletitled, Connecting the dots on connexin function

Journal Articles

The artificial intelligence revolution...in unethical publishing: Will AI worsen our dysfunctional publishing system?

Thiago F. A. França, José Maria Monserrat

J Gen Physiol (2024) 156 (11): e202413654.

https://doi.org/10.1085/jgp.202413654

Published: 07 October 2024

View articletitled, The artificial intelligence revolution...in unethical publishing: Will AI worsen our dysfunctional publishing system?

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Sensory neuron sodium channels as pain targets; from cocaine to Journavx (VX-548, suzetrigine)

A realistic look at rod synapses

How the Blind Watchmaker messed around with potassium channels

A complete set of rate constants for a transporter’s catalytic cycle

FAT3 provides a flicker of light

Structural and functional insights into α-actinin isoforms and their implications in cardiovascular disease

PANX1 hexamers work but cells prefer heptamers

JGP in 2025

Modeling cardiac contractile cooperativity across species

Inactivation of Ca_V1 and Ca_V2 channels

Understanding the role of mutations in voltage-gated sodium ion channels for cardiovascular disorders

How could simulations elucidate Na_v1.5 channel blockers mechanism?

How does mitochondrial Ca²⁺ change during ischemia and reperfusion? Implications for activation of the permeability transition pore

A misstep in the multistep process of fast inactivation

Time-dependent effect of FKBP12 loss in the development of dilated cardiomyopathy

A new stress test for ryanodine receptors

Myosin-binding protein-H: Not just filler

What happened to the pursuit of truth?

Connecting the dots on connexin function

The artificial intelligence revolution...in unethical publishing: Will AI worsen our dysfunctional publishing system?

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