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A controversial issue: Can mitochondria modulate cytosolic calcium and contraction of skeletal muscle fibers?

Carlo Reggiani, Lorenzo Marcucci

J Gen Physiol (2022) 154 (9): e202213167.

DOI: https://doi.org/10.1085/jgp.202213167

Published: 18 July 2022

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A scorpion toxin takes the sting out of T cell activation

Ben Short

J Gen Physiol (2022) 154 (8): e202213220.

DOI: https://doi.org/10.1085/jgp.202213220

Published: 11 July 2022

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How does flecainide impact RyR2 channel function?

Samantha C. Salvage, Christopher L.-H. Huang, James A. Fraser, Angela F. Dulhunty

J Gen Physiol (2022) 154 (9): e202213089.

DOI: https://doi.org/10.1085/jgp.202213089

Published: 17 June 2022

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How a tyrosine primes the pump

Ben Short

J Gen Physiol (2022) 154 (7): e202213199.

DOI: https://doi.org/10.1085/jgp.202213199

Published: 15 June 2022

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From α₁s splicing to γ₁ function: A new twist in subunit modulation of the skeletal muscle L-type Ca²⁺ channel

Werner Melzer

J Gen Physiol (2022) 154 (9): e202213182.

DOI: https://doi.org/10.1085/jgp.202213182

Published: 08 June 2022

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The surprising difficulty of “simple” equilibrium binding measurements on ligand-gated ion channels

Thomas R. Middendorf, Marcel P. Goldschen-Ohm

J Gen Physiol (2022) 154 (7): e202213177.

DOI: https://doi.org/10.1085/jgp.202213177

Published: 02 June 2022

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Do CPVT-linked mutations alter RYR2 regulation by cytosolic Ca²⁺ in cardiomyocytes?

Naohiro Yamaguchi

J Gen Physiol (2022) 154 (9): e202213078.

DOI: https://doi.org/10.1085/jgp.202213078

Published: 25 May 2022

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Journal Articles

Physics of mechanotransduction by Piezo ion channels

Michael Young, Amanda H. Lewis, Jörg Grandl

J Gen Physiol (2022) 154 (7): e202113044.

DOI: https://doi.org/10.1085/jgp.202113044

Published: 20 May 2022

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Journal Articles

Biophysical physiology of phosphoinositide rapid dynamics and regulation in living cells

Jill B. Jensen, Bjoern H. Falkenburger, Eamonn J. Dickson, Lizbeth de la Cruz, Gucan Dai, Jongyun Myeong, Seung-Ryoung Jung, Martin Kruse, Oscar Vivas, Byung-Chang Suh, Bertil Hille

J Gen Physiol (2022) 154 (6): e202113074.

DOI: https://doi.org/10.1085/jgp.202113074

Published: 18 May 2022

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ASIC3, a proton-gated ion channel with preference for polyunsaturated lipids with specific headgroup and tail properties

Sara I. Liin

J Gen Physiol (2022) 154 (7): e202213171.

DOI: https://doi.org/10.1085/jgp.202213171

Published: 18 May 2022

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A Kv2 inhibitor traps itself in place

Ben Short

J Gen Physiol (2022) 154 (6): e202213181.

DOI: https://doi.org/10.1085/jgp.202213181

Published: 06 May 2022

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Journal Articles

Biological noise is a key determinant of the reproducibility and adaptability of cardiac pacemaking and EC coupling

Laura Guarina, Ariana Neelufar Moghbel, Mohammad S. Pourhosseinzadeh, Robert H. Cudmore, Daisuke Sato, Colleen E. Clancy, Luis Fernando Santana

J Gen Physiol (2022) 154 (9): e202012613.

DOI: https://doi.org/10.1085/jgp.202012613

Published: 28 April 2022

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Journal Articles

X rays activate T cell calcium signaling

Ben Short

J Gen Physiol (2022) 154 (5): e202213163.

DOI: https://doi.org/10.1085/jgp.202213163

Published: 13 April 2022

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Gap junctions and hemichannels keep the RPE connected

Ben Short

J Gen Physiol (2022) 154 (4): e202213145.

DOI: https://doi.org/10.1085/jgp.202213145

Published: 18 March 2022

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Why are you talking with snakes? To get new evolutionary insights in cardiac electrophysiology!

Fabien Brette, Jean-Yves Le Guennec, Jérôme Thireau

J Gen Physiol (2022) 154 (4): e202113060.

DOI: https://doi.org/10.1085/jgp.202113060

Published: 17 March 2022

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Troponin levels make a difference

Ben Short

J Gen Physiol (2022) 154 (3): e202213119.

DOI: https://doi.org/10.1085/jgp.202213119

Published: 18 February 2022

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Journal Articles

Extracellular mechanotransduction

Stephen J. Haller, Andrew T. Dudley

J Gen Physiol (2022) 154 (3): e202113026.

DOI: https://doi.org/10.1085/jgp.202113026

Published: 16 February 2022

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Journal Articles

Catecholamines help snakes have a change of heart

Ben Short

J Gen Physiol (2022) 154 (2): e202213079.

DOI: https://doi.org/10.1085/jgp.202213079

Published: 21 January 2022

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Journal Articles

Functional and structural differences between skinned and intact muscle preparations

Alex Lewalle, Kenneth S. Campbell, Stuart G. Campbell, Gregory N. Milburn, Steven A. Niederer

J Gen Physiol (2022) 154 (2): e202112990.

DOI: https://doi.org/10.1085/jgp.202112990

Published: 19 January 2022

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Journal Articles

Sarcomere length in the beating heart: Synchronicity is optional

Michiel Helmes, Bradley M. Palmer

J Gen Physiol (2022) 154 (2): e202113022.

DOI: https://doi.org/10.1085/jgp.202113022

Published: 10 January 2022

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A controversial issue: Can mitochondria modulate cytosolic calcium and contraction of skeletal muscle fibers?

A scorpion toxin takes the sting out of T cell activation

How does flecainide impact RyR2 channel function?

How a tyrosine primes the pump

From α₁s splicing to γ₁ function: A new twist in subunit modulation of the skeletal muscle L-type Ca²⁺ channel

The surprising difficulty of “simple” equilibrium binding measurements on ligand-gated ion channels

Do CPVT-linked mutations alter RYR2 regulation by cytosolic Ca²⁺ in cardiomyocytes?

Physics of mechanotransduction by Piezo ion channels

Biophysical physiology of phosphoinositide rapid dynamics and regulation in living cells

ASIC3, a proton-gated ion channel with preference for polyunsaturated lipids with specific headgroup and tail properties

A Kv2 inhibitor traps itself in place

Biological noise is a key determinant of the reproducibility and adaptability of cardiac pacemaking and EC coupling

X rays activate T cell calcium signaling

Gap junctions and hemichannels keep the RPE connected

Why are you talking with snakes? To get new evolutionary insights in cardiac electrophysiology!

Troponin levels make a difference

Extracellular mechanotransduction

Catecholamines help snakes have a change of heart

Functional and structural differences between skinned and intact muscle preparations

Sarcomere length in the beating heart: Synchronicity is optional

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