-
Cover Image
Cover Image
Cover picture: Reverberation of excitation in 15 × 15 cluster of neurons caused by a stimulus applied to a single cell (red circles) located in the corner (top) or centrally (bottom). Light blue segments indicate electrical synapses exhibiting an asymmetry of I-V rectification. Colored isopotential areas show the spread of excitation (dashed arrows) from the core (dashed circles) of the reverberator (see Research Article by Maciunas et al., 273–288).
- PDF Icon PDF LinkTable of Contents
- PDF Icon PDF LinkEditorial Board
Article
Regulation of ENaC trafficking in rat kidney
In response to salt depletion, aldosterone drives the movement of Na channel protein from ER through the Golgi to the apical membrane in kidney epithelial cells.
Retigabine holds KV7 channels open and stabilizes the resting potential
Researchers studied the mechanism by which the anticonvulsant Retigabine enhances the activity of K+ channels and found that the drug stabilizes on open state at resting membrane potentials.
Multiple cytosolic calcium buffers in posterior pituitary nerve terminals
Researchers have measured the ability of nerve terminals to buffer Ca2+ entering in response to electrical activity to better understand plasticity of hormone release.
Contributions of protein kinases and β-arrestin to termination of protease-activated receptor 2 signaling
Systematic imaging studies and modeling reveal new details of the regulation of the Gq-coupled GPCR, protease-activated receptor 2, by phosphorylation and β-arrestin.
Reverberation of excitation in neuronal networks interconnected through voltage-gated gap junction channels
Voltage-dependent gap junction gating contributes to reverberation in neuronal circuits.
