Issues

Cover picture: FRET spectroscopy measurement of protein interactions in hERG K⁺ channels. Wide-field (left, top and bottom) and spectroscopic (middle, top and bottom) images of HEK293 cells coexpressing hERG N-terminal eag domains fused to CFP and hERG channels (with a deletion of the eag domain) fused to Citrine. (Right) Plot of spectroscopic data and spectral separation analysis indicating robust FRET between the two proteins (see research article by Gianulis et al., 351–366).