Issues
1 April 2009
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Cover Image
Cover Image
Cover picture: Fluorescence changes reveal rapid interactions between muscarinic receptor (M1R) and G proteins during receptor activation. (Top) Cartoon of expressed proteins in membrane: fluorescently labeled M1R-CFP and Gβ1-YFP and unlabeled Gαq and Gγ2. (Middle) Kinetics of M1R/Gβ1 interaction in a single cell. Blue and orange lines are fluorescence from M1R-CFP and Gβ1-YFP and the black line is their ratio. (Bottom) Averaged FRET timecourse from several cells (see article by Jensen et al., 347–359).
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ISSN 0022-1295
EISSN 1540-7748
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Voltage-Gated Na Channels
Drugs exhibit diverse binding modes and access routes in the Nav1.5 cardiac sodium channel pore
Mechanotransduction by Membrane Proteins
Mechanosensitive channel MscS is critical for termination of the bacterial hypoosmotic permeability response
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