Issues

Cover picture: Minimal model of the gating processes in MthK, which involves three conformational equilibria: pH-dependent assembly/disruption of the gating ring (state I and II); Ca²⁺/pH-dependent gating ring conformational shifts between open and closed states (state II and III), and Ca²⁺/pH-independent open/closed transitions of the channel pore (state III and IV) (see article by Li et al., 109–120).