Structure, function, and pharmacology of ion channels

We are pleased to present a collection of articles on the structure, function and pharmacology of ion channels, which have been curated from recent issues of JGP.

Ion channels are transmembrane proteins that are critical components of both excitable and non-excitable cells. Without ion channels, neurons would not be able to communicate with other cells, muscle would not be able to contract and our immune system would not be able to fight infection. Indeed, when ion channels go awry, disease often follows.

The articles in this collection provide fundamental insights into the structure, function and pharmacology of a number of different ligand- and voltage-gated ion channels. Such insights will ultimately support the development of new and specific drugs to target monogenic, multigenic, and acquired disease.

We hope you enjoy these articles, all of which are freely available for a limited period.

Image © 2019 Fryatt et al.