The phenomenological definition of active transport by Kedem and the methods of Kedem and Katchalsky have been used to obtain practical equations describing active transport in the single salt and bi-ionic systems. Procedures were devised to evaluate the required set of 10 coefficients for the single salt case and 15 for the bi-ionic. Three of these coefficients are unusual. They express the effects of active transport, i.e. of entrainment between metabolism and the conventional transport flows: active salt transport coefficient, a volume pump coefficient, and an electrogenicity coefficient. In the bi-ionic case a new passive coefficient, λ, was used to express the linkage between the fluxes of the two salts. However, if primary active transport involves only one ion, for example in the bi-ionic case, 12 coefficients suffice and certain relations can be predicted between the practical coefficients. Particular types of primary active transport could be identified by this means. The relation of active transport to membrane electrogenesis was also examined and the flux ratio equation was rederived in terms of the practical coefficients. Applications to specific parallel and series membrane systems have been analyzed.
Article|
January 01 1967
Phenomenological Description of Active Transport of Salt and Water
T. Hoshiko
,
T. Hoshiko
From the Department of Physiology, Western Reserve University, Cleveland, Ohio
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Barry D. Lindley
Barry D. Lindley
From the Department of Physiology, Western Reserve University, Cleveland, Ohio
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T. Hoshiko
From the Department of Physiology, Western Reserve University, Cleveland, Ohio
Barry D. Lindley
From the Department of Physiology, Western Reserve University, Cleveland, Ohio
Received:
February 21 1966
Online Issn: 1540-7748
Print Issn: 0022-1295
Copyright © 1967 by The Rockefeller University Press
1967
J Gen Physiol (1967) 50 (3): 729–758.
Article history
Received:
February 21 1966
Citation
T. Hoshiko, Barry D. Lindley; Phenomenological Description of Active Transport of Salt and Water . J Gen Physiol 1 January 1967; 50 (3): 729–758. doi: https://doi.org/10.1085/jgp.50.3.729
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