Diffusivity Measurements of Human Methemoglobin

Keller , K. H.; Friedlander , S. K.

doi:10.1085/jgp.49.4.681

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Article| March 01 1966

Diffusivity Measurements of Human Methemoglobin

K. H. Keller,

K. H. Keller

From the Department of Chemical Engineering, The Johns Hopkins University, Baltimore.

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S. K. Friedlander

From the Department of Chemical Engineering, The Johns Hopkins University, Baltimore.

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Author and Article Information

K. H. Keller

From the Department of Chemical Engineering, The Johns Hopkins University, Baltimore.

S. K. Friedlander

From the Department of Chemical Engineering, The Johns Hopkins University, Baltimore.

Dr. Keller's present address is the Department of Chemical Engineering, University of Minnesota, Minneapolis. Dr. Friedlander's present address is the W. M. Keck Engineering Laboratories, California Institute of Technology, Pasadena

Received: May 21 1965

Online ISSN: 1540-7748

Print ISSN: 0022-1295

1966

J Gen Physiol (1966) 49 (4): 681–687.

https://doi.org/10.1085/jgp.49.4.681

Experimental measurements of the diffusion coefficient of human methemoglobin were made at 25°C with a modified Stokes diaphragm diffusion cell. A Millipore filter was used in place of the ordinary fritted disc to facilitate rapid achievement of steady state in the diaphragm. Methemoglobin concentrations varied from approximately 5 g/100 ml to 30 g/100 ml. The diffusion coefficient in this range decreased from 7.5 x 10^-7 cm²/sec to 1.6 x 10^-7 cm²/sec.

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