In the preceding paper (1b) a formula was developed for the lowering of the fluidity of a medium by a mixture of proteins, given the volume concentration of each and its fluidity-lowering constant. Whole blood is now shown to follow an essentially similar formula, except that the hemoglobin content is taken from the literature as the best available measure of the volume of the blood cells Δ Φ = 0.24H, assuming the fluidity of the medium to be 53 rhes. Age, sex, diet, barometric pressure affect the hemoglobin content of the blood, but the formula may apply to any healthy human blood to about 3 per cent. The shape, number, and size of the blood cells, if known, might help to explain discrepancies as well as the state of oxidation of the blood. In disease the discrepancy becomes much greater, suggesting the possible use of rheology in diagnosis.
Article|
November 20 1944
THE RHEOLOGY OF THE BLOOD : IV. THE FLUIDITY OF WHOLE BLOOD AT 37°C.
Eugene C. Bingham
,
Eugene C. Bingham
From the Department of Chemistry, Lafayette College, Easton
Search for other works by this author on:
Raymond R. Roepke
Raymond R. Roepke
From the Department of Chemistry, Lafayette College, Easton
Search for other works by this author on:
Eugene C. Bingham
From the Department of Chemistry, Lafayette College, Easton
Raymond R. Roepke
From the Department of Chemistry, Lafayette College, Easton
Received:
June 13 1944
Online Issn: 1540-7748
Print Issn: 0022-1295
Copyright, 1944, by The Rockefeller Institute for Medical Research
1944
J Gen Physiol (1944) 28 (2): 131–149.
Article history
Received:
June 13 1944
Citation
Eugene C. Bingham, Raymond R. Roepke; THE RHEOLOGY OF THE BLOOD : IV. THE FLUIDITY OF WHOLE BLOOD AT 37°C. . J Gen Physiol 20 November 1944; 28 (2): 131–149. doi: https://doi.org/10.1085/jgp.28.2.131
Download citation file:
Close