In spite of obvious possible sources of disturbance, the "velocity of killing" of organisms at supranormal temperatures, properly determined, tends to adhere to the Arrhenius equation for relation to temperature. Over certain ranges of temperature the relationship between log velocity of killing and 1/T° abs. is linear. Interpreted as due to the thermal denaturing of protein, it is possible that differences between the temperature characteristics for the killing process in closely related forms may be suggestive in regard to the mechanism of the denaturing. The temperature limits within which the linear relationships appear may be classed among those temperature levels which are critical temperatures for protoplasmic organization.

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