The assumption that, at the equivalence point in specific precipitin reactions, the antigen molecule is completely covered with a single layer of antibody-globulin molecules has been shown to account fairly well for the antibody-antigen ratios of some representative native single proteins, and the pneumococcus S III hapten.
THE INFLUENCE OF THE MOLECULAR WEIGHT ANTIGEN ON THE PROPORTION OF ANTIBODY TO ANTIGEN IN PRECIPITATES
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William C. Boyd, Sanford B. Hooker; THE INFLUENCE OF THE MOLECULAR WEIGHT ANTIGEN ON THE PROPORTION OF ANTIBODY TO ANTIGEN IN PRECIPITATES . J Gen Physiol 20 January 1934; 17 (3): 341–348. doi: https://doi.org/10.1085/jgp.17.3.341
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