ON THE CALCULATION OF "TURNOVER TIME" AND "TURNOVER RATE" FROM EXPERIMENTS INVOLVING THE USE OF LABELING AGENTS

1. A new method for the determination of an immediate precursor of a substance occurring in the animal body is presented.

2. Calculations on the quantitative determination of the rate of turnover of a substance and their application to experiments involving the use of labeling agents are given. These calculations take into account loss of the isotopic substance by way of breakdown or transport.