1-20 of 25543
Journal Articles
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

In vivo antibody diversification targeting a conserved coronavirus epitope

Usha Nair, Ziqi Feng, Madhav Akauliya, Abigail G. Esposito, Charles R. Crain, Edward D. Lamperti, Thavaleak Prum, John E. Warner, Lisa Madungwe, Gordon A. Dale, Julie Boucau, Gaurav D. Gaiha, Meng Yuan, Ian A. Wilson, Facundo D. Batista
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (10): e20241563.
https://doi.org/10.1084/jem.20241563
Published: 17 July 2025
View article titled, In vivo antibody diversification targeting a conserved coronavirus epitope
Open the PDF for In vivo antibody diversification targeting a conserved coronavirus epitope in another window
Includes: Supplementary data
Journal Articles

Tumor-instructed glutamine synthesis in cancer-associated fibroblasts promotes pro-tumor macrophages

Xiaoyun Li, Sofie Hedlund Møller, Jaeoh Park, Yu-Ming Chuang, Pei-Chun Hsueh, Tzu-Hsuan Chang, Kung-Chi Kao, Hector Gallart-Ayala, Yi-Hao Wang, Jhan-Jie Peng, Alessio Bevilacqua, Yi-Ru Yu, Zhiyu Li, Yann Kieffer, Domitille Peigney, Hugo Croizer, Yingxi Xu, Alfred Zippelius, Isabel C. Lopez-Mejia, Lluis Fajas, Fatima Mechta-Grigoriou, Julijana Ivanisevic, Zhengtao Xiao, Ming-Chih Ho, Ying-Chun Shen, Ping-Chih Ho
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (9): e20241426.
https://doi.org/10.1084/jem.20241426
Published: 16 July 2025
View article titled, Tumor-instructed glutamine synthesis in cancer-associated fibroblasts promotes pro-tumor macrophages
Open the PDF for Tumor-instructed glutamine synthesis in cancer-associated fibroblasts promotes pro-tumor macrophages in another window
Includes: Supplementary data
Journal Articles

Monoallelic mutations in MMD2 cause autosomal dominant aggressive periodontitis

Tomoyuki Iwata, Yoko Mizoguchi, Tetsuya Yoshimoto, Miyuki Tsumura, Fumiaki Sakura, Jeffrey R. Johnson, Shinji Matsuda, Kazuhisa Ouhara, Yukiko Nagatani, Takaki Asano, Hidenori Ohnishi, Zenichiro Kato, Keichiro Mihara, Hirokazu Kanegane, Tomoya Ueda, Shinya Sasaki, Yuri Taniguchi, Yurika Ninomiya, Yoshinori Ohno, Kyoko Suzuki-Takedachi, Yusuke Sotomaru, Tetsushi Sakuma, Takashi Yamamoto, Yukiko Matsuda, Kodai Kume, Terukazu Sanui, Fusanori Nishimura, Mikihito Kajiya, Yasuyoshi Ueki, Hidemi Kurihara, Hiroyuki Morino, Satoshi Okada, Hideshi Kawakami, Noriyoshi Mizuno
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (9): e20231911.
https://doi.org/10.1084/jem.20231911
Published: 15 July 2025
View article titled, Monoallelic mutations in MMD2 cause autosomal dominant aggressive periodontitis
Open the PDF for Monoallelic mutations in MMD2 cause autosomal dominant aggressive periodontitis in another window
Includes: Supplementary data
Journal Articles

S1PR1, an endothelial-immune influencer

Samantha Mahfoud, Timothy P. Padera
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (9): e20251056.
https://doi.org/10.1084/jem.20251056
Published: 15 July 2025
View article titled, S1PR1, an endothelial-immune influencer
Open the PDF for S1PR1, an endothelial-immune influencer in another window
Journal Articles

Myeloid-targeting immunotherapies overcome inhibitory barriers in immune-evasive neuroblastoma

Marie Ménard, Hiroyuki Yoda, Nicole Nasholm, Megumi J. Barata, Linyu Wang, Erin F. Simonds, Edbert D. Lu, Shannon Wong-Michalak, Lauren McHenry, Alvin Farrel, Rebecca Kaufman, Vanessa Lopez, Rebekah J. Kennedy, G. Esteban Fernandez, Hiroyuki Shimada, Liron D. Grossmann, Shahab Asgharzadeh, John M. Maris, W. Clay Gustafson, William A. Weiss
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (9): e20231417.
https://doi.org/10.1084/jem.20231417
Published: 14 July 2025
View article titled, Myeloid-targeting immunotherapies overcome inhibitory barriers in immune-evasive neuroblastoma
Open the PDF for Myeloid-targeting immunotherapies overcome inhibitory barriers in immune-evasive neuroblastoma in another window
Includes: Supplementary data
Journal Articles

Taking the STING out of neurodegenerative disease

Aman Mangalmurti, John R. Lukens
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (10): e20250951.
https://doi.org/10.1084/jem.20250951
Published: 11 July 2025
View article titled, Taking the STING out of neurodegenerative disease
Open the PDF for Taking the STING out of neurodegenerative disease in another window
Journal Articles

The STING pathway drives noninflammatory neurodegeneration in NGLY1 deficiency

Kun Yang, Gustavo Torres-Ramirez, Nicole Dobbs, Jie Han, Makoto Asahina, Reiko Fujinawa, Kun Song, Yun Liu, Weichun Lin, Angelica Oviedo, Chuo Chen, Lei Zhu, William F. Mueller, Kevin Lee, Tadashi Suzuki, Nan Yan
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (10): e20242296.
https://doi.org/10.1084/jem.20242296
Published: 11 July 2025
View article titled, The STING pathway drives noninflammatory neurodegeneration in NGLY1 deficiency
Open the PDF for The STING pathway drives noninflammatory neurodegeneration in NGLY1 deficiency in another window
Includes: Supplementary data
Journal Articles

Bone marrow neutrophil density regulates myelopoiesis during obesity and weight loss

Quin T. Waterbury, Jin Qian, Hualong Zheng, Amanda Dirnberger, Oakley C. Olson, Ruth A. White, Feijing Wu, Hiroki Kobayashi, Ermanno Malagola, Yosuke Ochiai, Ruhong Tu, Biyun Zheng, Adama Diaby, Harry Nagendra, Jonathan S. LaBella, Leah Zamechek, Judith Korner, Ana B. Emiliano, Anthony W. Ferrante, Jr., Emmanuelle Passegué, Timothy C. Wang
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (9): e20242174.
https://doi.org/10.1084/jem.20242174
Published: 11 July 2025
View article titled, Bone marrow neutrophil density regulates myelopoiesis during obesity and weight loss
Open the PDF for Bone marrow neutrophil density regulates myelopoiesis during obesity and weight loss in another window
Includes: Supplementary data
Journal Articles

Epitope and HLA specificity of human TCRs against Plasmodium falciparum circumsporozoite protein

In Special Collection:
Journal-Based CME Activities with Journal of Experimental Medicine (JEM)
Hannah van Dijk, Ilka Wahl, Sara Kraker, Paul M. Robben, Sheetij Dutta, Hedda Wardemann
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (9): e20250044.
https://doi.org/10.1084/jem.20250044
Published: 10 July 2025
View article titled, Epitope and HLA specificity of human TCRs against Plasmodium falciparum circumsporozoite protein
Open the PDF for Epitope and HLA specificity of human TCRs against Plasmodium falciparum circumsporozoite protein in another window
Includes: Supplementary data
Journal Articles

Gut microbiota–derived TMAVA is a modulator of acute CNS-GVHD

Sangya Chatterjee, Tamina Rückert, Ina Martin, Elisa Michaeli, Joerg Buescher, Petya Apostolova, Daniel Erny, Maria-Eleni Lalioti, Francesca Biavasco, Alina Hartmann, Solveig Runge, Lukas M. Braun, Nana Talvard-Balland, Rachael C. Adams, Annette Schmitt-Graeff, James Cook, Valentin Wenger, Dimitrios Athanassopoulos, Dilara Hasavci, Alexander Paolo Vallejo-Janeta, Thomas Blank, Philipp Schaible, Janaki Manoja Vinnakota, Alexander Zähringer, Stephanie C. Ganal-Vonarburg, Wolfgang Melchinger, Dietmar Pfeifer, Natalie Köhler, Stephan P. Rosshart, David Michonneau, Gérard Socié, Geoffroy Andrieux, Nina Cabezas-Wallscheid, Melanie Boerries, Marco Prinz, Robert Zeiser
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (9): e20242180.
https://doi.org/10.1084/jem.20242180
Published: 08 July 2025
View article titled, Gut microbiota–derived TMAVA is a modulator of acute CNS-GVHD
Open the PDF for Gut microbiota–derived TMAVA is a modulator of acute CNS-GVHD in another window
Journal Articles

Adipose tissue harbors pathogenic T cells in obesity that exacerbate inflammatory arthritis

Heather J. Faust, Margaret H. Chang, A. Helena Jonsson, Erin Theisen, Nelson M. LaMarche, William V. Trim, Lydia Lynch, Peter A. Nigrovic, Michael B. Brenner
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (9): e20240677.
https://doi.org/10.1084/jem.20240677
Published: 07 July 2025
View article titled, Adipose tissue harbors pathogenic T cells in obesity that exacerbate inflammatory arthritis
Open the PDF for Adipose tissue harbors pathogenic T cells in obesity that exacerbate inflammatory arthritis in another window
Includes: Supplementary data
Journal Articles

Histidine decarboxylase inhibition attenuates cancer-associated muscle wasting

Aneesha Dasgupta, Rebecca E. Schmitt, Tatsuyoshi Kono, Chih-Chun Lee, Mark I. Zoberi, Savannah A. Epstein, Jessica Z. Schneider, Alejandro Hernandez, Paul M. Grandgenett, Thomas C. Caffrey, Dominick J. DiMaio, Michael A. Hollingsworth, Jason D. Doles
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (9): e20242239.
https://doi.org/10.1084/jem.20242239
Published: 02 July 2025
View article titled, Histidine decarboxylase inhibition attenuates cancer-associated muscle wasting
Open the PDF for Histidine decarboxylase inhibition attenuates cancer-associated muscle wasting in another window
Journal Articles

Expression of Concern: ΔNp73, A Dominant-Negative Inhibitor of Wild-type p53 and TAp73, Is Up-regulated in Human Tumors

Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (7): e2002017906102025e.
https://doi.org/10.1084/jem.2002017906102025e
Published: 27 June 2025
View article titled, Expression of Concern: ΔNp73, A Dominant-Negative Inhibitor of Wild-type p53 and TAp73, Is Up-regulated in Human Tumors
Open the PDF for Expression of Concern: ΔNp73, A Dominant-Negative Inhibitor of Wild-type p53 and TAp73, Is Up-regulated in Human Tumors in another window
Journal Articles

Correction: ICAM-1 controls development and function of ILC2

Ai-Hua Lei, Qiang Xiao, Gao-Yu Liu, Kun Shi, Qiong Yang, Xing Li, Yu-Feng Liu, Hai-Kun Wang, Wei-Ping Cai, Yu-Juan Guan, Dmitry I. Gabrilovich, Jie Zhou
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (7): e2017235906182025c.
https://doi.org/10.1084/jem.2017235906182025c
Published: 25 June 2025
View article titled, Correction: ICAM-1 controls development and function of ILC2
Open the PDF for Correction: ICAM-1 controls development and function of ILC2 in another window
Journal Articles

S1PR1 regulates lymphatic valve development and tertiary lymphoid organ formation in the ileum

Xin Geng, Lijuan Chen, Zoheb Ahmed, Guilherme Pedron Formigari, Yen-Chun Ho, Ilaria Del Gaudio, Marcella Neves Datilo, Zheila J. Azartash-Namin, Coraline Heron, Xindi Shan, Ravi Shankar Keshari, Soumiya Pal, Hong Chen, Florea Lupu, Lijun Xia, Gwendalyn J. Randolph, Scott D. Zawieja, Eric Camerer, Michael J. Davis, R. Sathish Srinivasan
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (9): e20241799.
https://doi.org/10.1084/jem.20241799
Published: 24 June 2025
View article titled, S1PR1 regulates lymphatic valve development and tertiary lymphoid organ formation in the ileum
Open the PDF for S1PR1 regulates lymphatic valve development and tertiary lymphoid organ formation in the ileum in another window
Includes: Supplementary data
Journal Articles

Costimulatory connections: CARMIL2 and CD28

Lawrence P. Kane
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (8): e20250896.
https://doi.org/10.1084/jem.20250896
Published: 20 June 2025
View article titled, Costimulatory connections: CARMIL2 and CD28
Open the PDF for Costimulatory connections: CARMIL2 and CD28 in another window
Journal Articles

Correction: Mitophagy-mediated adipose inflammation contributes to type 2 diabetes with hepatic insulin resistance

Feng He, Yanrui Huang, Zhi Song, Huanjiao Jenny Zhou, Haifeng Zhang, Rachel J. Perry, Gerald I. Shulman, Wang Min
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (7): e2020141606022025c.
https://doi.org/10.1084/jem.2020141606022025c
Published: 13 June 2025
View article titled, Correction: Mitophagy-mediated adipose inflammation contributes to type 2 diabetes with hepatic insulin resistance
Open the PDF for Correction: Mitophagy-mediated adipose inflammation contributes to type 2 diabetes with hepatic insulin resistance in another window
Journal Articles

Intestinal lymphatic vasculature is functionally adapted to different drainage regions and is altered by helminth infection

Jorden I. Lane, Elida Nieves-Ortiz, Ornella Ndatabaye, Aliia R. Fatkhullina, Sebastian Lopez, Terence S. Dermody, Daria Esterházy
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (9): e20241181.
https://doi.org/10.1084/jem.20241181
Published: 12 June 2025
View article titled, Intestinal lymphatic vasculature is functionally adapted to different drainage regions and is altered by helminth infection
Open the PDF for Intestinal lymphatic vasculature is functionally adapted to different drainage regions and is altered by helminth infection in another window
Includes: Supplementary data
Journal Articles

Membrane-IL12 adjuvant mRNA vaccine polarizes pre-effector T cells for optimized tumor control

Kun Peng, Xiaoxue Zhao, Hongjian Li, Yang-Xin Fu, Yong Liang
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (9): e20241454.
https://doi.org/10.1084/jem.20241454
Published: 06 June 2025
View article titled, Membrane-IL12 adjuvant mRNA vaccine polarizes pre-effector T cells for optimized tumor control
Open the PDF for Membrane-IL12 adjuvant mRNA vaccine polarizes pre-effector T cells for optimized tumor control in another window
Journal Articles

Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis

Riem Gawish, Rajagopal Varada, Florian Deckert, Anastasiya Hladik, Linda Steinbichl, Laura Cimatti, Katarina Milanovic, Mamta Jain, Natalya Torgasheva, Andrea Tanzer, Kim De Paepe, Tom Van de Wiele, Bela Hausmann, Michaela Lang, Martin Pechhacker, Nahla Ibrahim, Ingrid De Vries, Christine Brostjan, Michael Sixt, Christoph Gasche, Louis Boon, David Berry, Michael F. Jantsch, Fatima C. Pereira, Cornelia Vesely
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (9): e20240109.
https://doi.org/10.1084/jem.20240109
Published: 05 June 2025
View article titled, Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis
Open the PDF for Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis in another window
Includes: Supplementary data