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Journal Articles

Hypoxia is linked to acquired resistance to immune checkpoint inhibitors in lung cancer

Camila Robles-Oteíza, Katherine Hastings, Jungmin Choi, Isabelle Sirois, Arvind Ravi, Francisco Expósito, Fernando de Miguel, James R. Knight, Francesc López-Giráldez, Hyejin Choi, Nicholas D. Socci, Taha Merghoub, Mark Awad, Gad Getz, Justin Gainor, Matthew D. Hellmann, Étienne Caron, Susan M. Kaech, Katerina Politi

J Exp Med (2024) 222 (1): e20231106.

https://doi.org/10.1084/jem.20231106

Published: 25 November 2024

View article titled, Hypoxia is linked to acquired resistance to immune checkpoint inhibitors in lung cancer

Includes: Supplementary data

Journal Articles

ACLY and ACSS2 link nutrient-dependent chromatin accessibility to CD8 T cell effector responses

J Exp Med (2024) 221 (9): e20231820.

https://doi.org/10.1084/jem.20231820

Published: 16 August 2024

View article titled, ACLY and ACSS2 link nutrient-dependent chromatin accessibility to CD8 T cell effector responses

Includes: Supplementary data

Journal Articles

Clonal lineage tracing reveals mechanisms skewing CD8⁺ T cell fate decisions in chronic infection

Moujtaba Y. Kasmani, Ryan Zander, H. Kay Chung, Yao Chen, Achia Khatun, Martina Damo, Paytsar Topchyan, Kaitlin E. Johnson, Darya Levashova, Robert Burns, Ulrike M. Lorenz, Vera L. Tarakanova, Nikhil S. Joshi, Susan M. Kaech, Weiguo Cui

J Exp Med (2022) 220 (1): e20220679.

https://doi.org/10.1084/jem.20220679

Published: 31 October 2022

View article titled, Clonal lineage tracing reveals mechanisms skewing CD8+ T cell fate decisions in chronic infection

Journal Articles

The architectural design of CD8⁺ T cell responses in acute and chronic infection: Parallel structures with divergent fates

H. Kay Chung, Bryan McDonald, Susan M. Kaech

J Exp Med (2021) 218 (4): e20201730.

https://doi.org/10.1084/jem.20201730

Published: 23 March 2021

View article titled, The architectural design of CD8+ T cell responses in acute and chronic infection: Parallel structures with divergent fates

Journal Articles

Immigration in science

Jean-Laurent Casanova, David M. Holtzman, Susan M. Kaech, Lewis L. Lanier, Carl F. Nathan, Alexander Y. Rudensky, David Tuveson, Jedd D. Wolchok

J Exp Med (2020) 217 (11): e20202055.

https://doi.org/10.1084/jem.20202055

Published: 15 October 2020

View article titled, Immigration in science

Journal Articles

Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses

In Special Collection:

2020: The Year in Experimental Medicine

Jun Siong Low, Yagmur Farsakoglu, Maria Carolina Amezcua Vesely, Esen Sefik, Joseph B. Kelly, Christian C.D. Harman, Ruaidhri Jackson, Justin A. Shyer, Xiaodong Jiang, Linda S. Cauley, Richard A. Flavell, Susan M. Kaech

J Exp Med (2020) 217 (8): e20192291.

https://doi.org/10.1084/jem.20192291

Published: 11 June 2020

View article titled, Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses

Journal Articles

T-bet in Tfh cells: Now you see me, now you don’t

Susan M. Kaech

J Exp Med (2018) 215 (11): 2697–2698.

https://doi.org/10.1084/jem.20181878

Published: 18 October 2018

View article titled, T-bet in Tfh cells: Now you see me, now you don’t

Journal Articles

ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8⁺ T cell fates

In Special Collection:

T Cell Memory: Epigenetics, Regulation, and Immunotherapy

Tianxia Guan, Claudia X. Dominguez, Robert A. Amezquita, Brian J. Laidlaw, Jijun Cheng, Jorge Henao-Mejia, Adam Williams, Richard A. Flavell, Jun Lu, Susan M. Kaech

J Exp Med (2018) 215 (4): 1153–1168.

https://doi.org/10.1084/jem.20171352

Published: 15 February 2018

View article titled, ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8+ T cell fates

Includes: Supplementary data

Journal Articles

Correction: STAT4 and T-bet control follicular helper T cell development in viral infections

Jason S. Weinstein, Brian J. Laidlaw, Yisi Lu, Jessica K. Wang, Vincent P. Schulz, Ningcheng Li, Edward I. Herman, Susan M. Kaech, Patrick G. Gallagher, Joe Craft

J Exp Med (2018) 215 (3): 999.

https://doi.org/10.1084/jem.2017045702062018c

Published: 13 February 2018

View article titled, Correction: STAT4 and T-bet control follicular helper T cell development in viral infections

Journal Articles

Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity

In Special Collection:

Cancer and Autoimmunity , Cancer Metastasis 2019 , Innate and Non-classical Immune Cells in Tumor Progression and Cancer Immunotherapy 2019 , JEM Cancer Collection 2019 , JEM Immunology Collection 2019 , Myeloid Cells 2018

Curtis J. Perry, Andrés R. Muñoz-Rojas, Katrina M. Meeth, Laura N. Kellman, Robert A. Amezquita, Durga Thakral, Victor Y. Du, Jake Xiao Wang, William Damsky, Alexandra L. Kuhlmann, Joel W. Sher, Marcus Bosenberg, Kathryn Miller-Jensen, Susan M. Kaech

J Exp Med (2018) 215 (3): 877–893.

https://doi.org/10.1084/jem.20171435

Published: 07 February 2018

View article titled, Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity

Includes: Supplementary data

Journal Articles

STAT4 and T-bet control follicular helper T cell development in viral infections

Jason S. Weinstein, Brian J. Laidlaw, Yisi Lu, Jessica K. Wang, Vincent P. Schulz, Ningcheng Li, Edward I. Herman, Susan M. Kaech, Patrick G. Gallagher, Joe Craft

J Exp Med (2017) 215 (1): 337–355.

https://doi.org/10.1084/jem.20170457

Published: 06 December 2017

View article titled, STAT4 and T-bet control follicular helper T cell development in viral infections

Includes: Supplementary data

Journal Articles

The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection

In Special Collection:

T Cell Dysfunction, Cancer, and Infection

Claudia X. Dominguez, Robert A. Amezquita, Tianxia Guan, Heather D. Marshall, Nikhil S. Joshi, Steven H. Kleinstein, Susan M. Kaech

J Exp Med (2015) 212 (12): 2041–2056.

https://doi.org/10.1084/jem.20150186

Published: 26 October 2015

View article titled, The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection

Journal Articles

Estimating the Precursor Frequency of Naive Antigen-specific CD8 T Cells

Joseph N. Blattman, Rustom Antia, David J.D. Sourdive, Xiaochi Wang, Susan M. Kaech, Kaja Murali-Krishna, John D. Altman, Rafi Ahmed

J Exp Med (2002) 195 (5): 657–664.

https://doi.org/10.1084/jem.20001021

Published: 04 March 2002

View article titled, Estimating the Precursor Frequency of Naive Antigen-specific CD8 T Cells

NARROW

Hypoxia is linked to acquired resistance to immune checkpoint inhibitors in lung cancer

ACLY and ACSS2 link nutrient-dependent chromatin accessibility to CD8 T cell effector responses

Clonal lineage tracing reveals mechanisms skewing CD8⁺ T cell fate decisions in chronic infection

The architectural design of CD8⁺ T cell responses in acute and chronic infection: Parallel structures with divergent fates

Immigration in science

Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses

T-bet in Tfh cells: Now you see me, now you don’t

ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8⁺ T cell fates

Correction: STAT4 and T-bet control follicular helper T cell development in viral infections

Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity

STAT4 and T-bet control follicular helper T cell development in viral infections

The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection

Estimating the Precursor Frequency of Naive Antigen-specific CD8 T Cells

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