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Ralf Küppers
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Journal Articles

The life of B cells according to JEM

Ralf Küppers
Journal: Journal of Experimental Medicine
Series: JEM 125th Anniversary
J Exp Med (2021) 218 (5): e20210647.
https://doi.org/10.1084/jem.20210647
Published: 21 April 2021
View article titled, The life of B cells according to <em>JEM</em>
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Journal Articles

Systematic memory B cell archiving and random display shape the human splenic marginal zone throughout life

Artur Kibler, Bettina Budeus, Ekaterina Homp, Kevin Bronischewski, Victoria Berg, Ludger Sellmann, Florian Murke, Andreas Heinold, Falko M. Heinemann, Monika Lindemann, Isabelle Bekeredjian-Ding, Peter A. Horn, Carsten J. Kirschning, Ralf Küppers, Marc Seifert
Journal: Journal of Experimental Medicine
J Exp Med (2021) 218 (4): e20201952.
https://doi.org/10.1084/jem.20201952
Published: 04 February 2021
View article titled, Systematic memory B cell archiving and random display shape the human splenic marginal zone throughout life
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Includes: Supplementary data
Journal Articles

CD81 as target for B cell lymphomas

Ralf Küppers
Journal: Journal of Experimental Medicine
J Exp Med (2019) 216 (7): 1469–1470.
https://doi.org/10.1084/jem.20190733
Published: 06 June 2019
View article titled, CD81 as target for B cell lymphomas
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Journal Articles

IRAK4 inhibition to shut down TLR signaling in autoimmunity and MyD88-dependent lymphomas

Ralf Küppers
Journal: Journal of Experimental Medicine
J Exp Med (2015) 212 (13): 2184.
https://doi.org/10.1084/jem.21213insight1
Published: 14 December 2015
View article titled, IRAK4 inhibition to shut down TLR signaling in autoimmunity and MyD88-dependent lymphomas
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Journal Articles

Cellular origin and pathophysiology of chronic lymphocytic leukemia

Marc Seifert, Ludger Sellmann, Johannes Bloehdorn, Frederik Wein, Stephan Stilgenbauer, Jan Dürig, Ralf Küppers
Journal: Journal of Experimental Medicine
J Exp Med (2012) 209 (12): 2183–2198.
https://doi.org/10.1084/jem.20120833
Published: 22 October 2012
View article titled, Cellular origin and pathophysiology of chronic lymphocytic leukemia
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Includes: Supplementary data
Journal Articles

Molecular footprints of a germinal center derivation of human IgM+(IgD+)CD27+ B cells and the dynamics of memory B cell generation

Marc Seifert, Ralf Küppers
Journal: Journal of Experimental Medicine
J Exp Med (2009) 206 (12): 2659–2669.
https://doi.org/10.1084/jem.20091087
Published: 16 November 2009
View article titled, Molecular footprints of a germinal center derivation of human IgM<sup>+</sup>(IgD<sup>+</sup>)CD27<sup>+</sup> B cells and the dynamics of memory B cell generation
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Includes: Supplementary data
Journal Articles

TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma

Roland Schmitz, Martin-Leo Hansmann, Verena Bohle, Jose Ignacio Martin-Subero, Sylvia Hartmann, Gunhild Mechtersheimer, Wolfram Klapper, Inga Vater, Maciej Giefing, Stefan Gesk, Jens Stanelle, Reiner Siebert, Ralf Küppers
Journal: Journal of Experimental Medicine
J Exp Med (2009) 206 (5): 981–989.
https://doi.org/10.1084/jem.20090528
Published: 20 April 2009
View article titled, <em>TNFAIP3</em> (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma
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Includes: Supplementary data
Journal Articles

Survival and Clonal Expansion of Mutating “Forbidden” (Immunoglobulin Receptor–Deficient) Epstein-Barr Virus–Infected B Cells in Angioimmunoblastic T Cell Lymphoma

Andreas Bräuninger, Tilmann Spieker, Klaus Willenbrock, Philippe Gaulard, Hans-Heinrich Wacker, Klaus Rajewsky, Martin-Leo Hansmann, Ralf Küppers
Journal: Journal of Experimental Medicine
J Exp Med (2001) 194 (7): 927–940.
https://doi.org/10.1084/jem.194.7.927
Published: 01 October 2001
View article titled, Survival and Clonal Expansion of Mutating “Forbidden” (Immunoglobulin Receptor–Deficient) Epstein-Barr Virus–Infected B Cells in Angioimmunoblastic T Cell Lymphoma
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Journal Articles

Somatic Mutation of the Cd95 Gene in Human B Cells as a Side-Effect of the Germinal Center Reaction

Markus Müschen, Daniel Re, Berit Jungnickel, Volker Diehl, Klaus Rajewsky, Ralf Küppers
Journal: Journal of Experimental Medicine
J Exp Med (2000) 192 (12): 1833–1840.
https://doi.org/10.1084/jem.192.12.1833
Published: 18 December 2000
View article titled, Somatic Mutation of the Cd95 Gene in Human B Cells as a Side-Effect of the Germinal Center Reaction
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Journal Articles

Clonal Deleterious Mutations in the Iκbα Gene in the Malignant Cells in Hodgkin's Lymphoma

Berit Jungnickel, Andrea Staratschek-Jox, Andreas Bräuninger, Tilmann Spieker, Jürgen Wolf, Volker Diehl, Martin-Leo Hansmann, Klaus Rajewsky, Ralf Küppers
Journal: Journal of Experimental Medicine
J Exp Med (2000) 191 (2): 395–402.
https://doi.org/10.1084/jem.191.2.395
Published: 17 January 2000
View article titled, Clonal Deleterious Mutations in the Iκbα Gene in the Malignant Cells in Hodgkin's Lymphoma
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Journal Articles

Rare Occurrence of Classical Hodgkin's Disease as a T Cell Lymphoma

Markus Müschen, Klaus Rajewsky, Andreas Bräuninger, Audrey Sylvia Baur, Joost J. Oudejans, Axel Roers, Martin-Leo Hansmann, Ralf Küppers
Journal: Journal of Experimental Medicine
J Exp Med (2000) 191 (2): 387–394.
https://doi.org/10.1084/jem.191.2.387
Published: 17 January 2000
View article titled, Rare Occurrence of Classical Hodgkin's Disease as a T Cell Lymphoma
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Journal Articles

Human Immunoglobulin (Ig)M+IgD+ Peripheral Blood B Cells Expressing the CD27 Cell Surface Antigen Carry Somatically Mutated Variable Region Genes: CD27 as a General Marker for Somatically Mutated (Memory) B Cells

Ulf Klein, Klaus Rajewsky, Ralf Küppers
Journal: Journal of Experimental Medicine
J Exp Med (1998) 188 (9): 1679–1689.
https://doi.org/10.1084/jem.188.9.1679
Published: 02 November 1998
View article titled, Human Immunoglobulin (Ig)M<sup>+</sup>IgD<sup>+</sup> Peripheral Blood B Cells Expressing the CD27 Cell Surface Antigen Carry Somatically Mutated Variable Region Genes: CD27 as a General Marker for Somatically Mutated (Memory) B Cells
Open the PDF for Human Immunoglobulin (Ig)M<sup>+</sup>IgD<sup>+</sup> Peripheral Blood B Cells Expressing the CD27 Cell Surface Antigen Carry Somatically Mutated Variable Region Genes: CD27 as a General Marker for Somatically Mutated (Memory) B Cells in another window