Page 1 | Search Results | Journal of Experimental Medicine

Skip Nav Destination

1-20 of 35

Sort by

Sort Order Select

Journal Articles

Evidence that binding site occupancy is necessary and sufficient for effective major histocompatibility complex (MHC) class II transport through the secretory pathway redefines the primary function of class II-associated invariant chain peptides (CLIP).

G Zhong, F Castellino, P Romagnoli, R N Germain

J Exp Med (1996) 184 (5): 2061–2066.

https://doi.org/10.1084/jem.184.5.2061

Published: 01 November 1996

View article titled, Evidence that binding site occupancy is necessary and sufficient for effective major histocompatibility complex (MHC) class II transport through the secretory pathway redefines the primary function of class II-associated invariant chain peptides (CLIP).

Journal Articles

Partial signaling by CD8+ T cells in response to antagonist ligands.

C Reis e Sousa, E H Levine, R N Germain

J Exp Med (1996) 184 (1): 149–157.

https://doi.org/10.1084/jem.184.1.149

Published: 01 July 1996

View article titled, Partial signaling by CD8+ T cells in response to antagonist ligands.

Journal Articles

Inhibition of invariant chain (Ii)-calnexin interaction results in enhanced degradation of Ii but does not prevent the assembly of alpha beta Ii complexes.

P Romagnoli, R N Germain

J Exp Med (1995) 182 (6): 2027–2036.

https://doi.org/10.1084/jem.182.6.2027

Published: 01 December 1995

View article titled, Inhibition of invariant chain (Ii)-calnexin interaction results in enhanced degradation of Ii but does not prevent the assembly of alpha beta Ii complexes.

Journal Articles

Involvement of both major histocompatibility complex class II alpha and beta chains in CD4 function indicates a role for ordered oligomerization in T cell activation.

R König, X Shen, R N Germain

J Exp Med (1995) 182 (3): 779–787.

https://doi.org/10.1084/jem.182.3.779

Published: 01 September 1995

View article titled, Involvement of both major histocompatibility complex class II alpha and beta chains in CD4 function indicates a role for ordered oligomerization in T cell activation.

Journal Articles

Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis.

C Reis e Sousa, R N Germain

J Exp Med (1995) 182 (3): 841–851.

https://doi.org/10.1084/jem.182.3.841

Published: 01 September 1995

View article titled, Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis.

Journal Articles

The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancy.

P Romagnoli, R N Germain

J Exp Med (1994) 180 (3): 1107–1113.

https://doi.org/10.1084/jem.180.3.1107

Published: 01 September 1994

View article titled, The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancy.

Journal Articles

CD28-mediated costimulation of interleukin 2 (IL-2) production plays a critical role in T cell priming for IL-4 and interferon gamma production.

R A Seder, R N Germain, P S Linsley, W E Paul

J Exp Med (1994) 179 (1): 299–304.

https://doi.org/10.1084/jem.179.1.299

Published: 01 January 1994

View article titled, CD28-mediated costimulation of interleukin 2 (IL-2) production plays a critical role in T cell priming for IL-4 and interferon gamma production.

Journal Articles

Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression.

E K Bikoff, L Y Huang, V Episkopou, J van Meerwijk, R N Germain, E J Robertson

J Exp Med (1993) 177 (6): 1699–1712.

https://doi.org/10.1084/jem.177.6.1699

Published: 01 June 1993

View article titled, Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression.

Journal Articles

Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signaling.

L Racioppi, F Ronchese, L A Matis, R N Germain

J Exp Med (1993) 177 (4): 1047–1060.

https://doi.org/10.1084/jem.177.4.1047

Published: 01 April 1993

View article titled, Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signaling.

Journal Articles

Relationship between invariant chain expression and major histocompatibility complex class II transport into early and late endocytic compartments.

P Romagnoli, C Layet, J Yewdell, O Bakke, R N Germain

J Exp Med (1993) 177 (3): 583–596.

https://doi.org/10.1084/jem.177.3.583

Published: 01 March 1993

View article titled, Relationship between invariant chain expression and major histocompatibility complex class II transport into early and late endocytic compartments.

Journal Articles

Serum angiotensin-1 converting enzyme activity processes a human immunodeficiency virus 1 gp160 peptide for presentation by major histocompatibility complex class I molecules.

S Kozlowski, M Corr, T Takeshita, L F Boyd, C D Pendleton, R N Germain, J A Berzofsky, D H Margulies

J Exp Med (1992) 175 (6): 1417–1422.

https://doi.org/10.1084/jem.175.6.1417

Published: 01 June 1992

View article titled, Serum angiotensin-1 converting enzyme activity processes a human immunodeficiency virus 1 gp160 peptide for presentation by major histocompatibility complex class I molecules.

Journal Articles

Presentation of antigen by mixed isotype class II molecules in normal H-2d mice.

G Ruberti, K S Sellins, C M Hill, R N Germain, C G Fathman, A Livingstone

J Exp Med (1992) 175 (1): 157–162.

https://doi.org/10.1084/jem.175.1.157

Published: 01 January 1992

View article titled, Presentation of antigen by mixed isotype class II molecules in normal H-2d mice.

Journal Articles

Defective intracellular transport as a common mechanism limiting expression of inappropriately paired class II major histocompatibility complex alpha/beta chains.

A J Sant, L R Hendrix, J E Coligan, W L Maloy, R N Germain

J Exp Med (1991) 174 (4): 799–808.

https://doi.org/10.1084/jem.174.4.799

Published: 01 October 1991

View article titled, Defective intracellular transport as a common mechanism limiting expression of inappropriately paired class II major histocompatibility complex alpha/beta chains.

Journal Articles

An immunodominant class I-restricted cytotoxic T lymphocyte determinant of human immunodeficiency virus type 1 induces CD4 class II-restricted help for itself.

H Takahashi, R N Germain, B Moss, J A Berzofsky

J Exp Med (1990) 171 (2): 571–576.

https://doi.org/10.1084/jem.171.2.571

Published: 01 February 1990

View article titled, An immunodominant class I-restricted cytotoxic T lymphocyte determinant of human immunodeficiency virus type 1 induces CD4 class II-restricted help for itself.

Journal Articles

Structural requirements for class I MHC molecule-mediated antigen presentation and cytotoxic T cell recognition of an immunodominant determinant of the human immunodeficiency virus envelope protein.

H Takahashi, R Houghten, S D Putney, D H Margulies, B Moss, R N Germain, J A Berzofsky

J Exp Med (1989) 170 (6): 2023–2035.

https://doi.org/10.1084/jem.170.6.2023

Published: 01 December 1989

View article titled, Structural requirements for class I MHC molecule-mediated antigen presentation and cytotoxic T cell recognition of an immunodominant determinant of the human immunodeficiency virus envelope protein.

Journal Articles

The contribution of mutant amino acids to alloantigenicity.

J Bill, F Ronchese, R N Germain, E Palmer

J Exp Med (1989) 170 (3): 739–750.

https://doi.org/10.1084/jem.170.3.739

Published: 01 September 1989

View article titled, The contribution of mutant amino acids to alloantigenicity.

Journal Articles

Surface expression of only gamma delta and/or alpha beta T cell receptor heterodimers by cells with four (alpha, beta, gamma, delta) functional receptor chains.

T Saito, F Hochstenbach, S Marusic-Galesic, A M Kruisbeek, M Brenner, R N Germain

J Exp Med (1988) 168 (3): 1003–1020.

https://doi.org/10.1084/jem.168.3.1003

Published: 01 September 1988

View article titled, Surface expression of only gamma delta and/or alpha beta T cell receptor heterodimers by cells with four (alpha, beta, gamma, delta) functional receptor chains.

Journal Articles

Early genetic events in T cell development analyzed by in situ hybridization.

D M Pardoll, B J Fowlkes, R I Lechler, R N Germain, R H Schwartz

J Exp Med (1987) 165 (6): 1624–1638.

https://doi.org/10.1084/jem.165.6.1624

Published: 01 June 1987

View article titled, Early genetic events in T cell development analyzed by in situ hybridization.

Journal Articles

Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain.

J Miller, R N Germain

J Exp Med (1986) 164 (5): 1478–1489.

https://doi.org/10.1084/jem.164.5.1478

Published: 01 November 1986

View article titled, Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain.

Journal Articles

I-A-restricted T cell antigen recognition. Analysis of the roles of A alpha and A beta using DNA-mediated gene transfer.

R I Lechler, F Ronchese, N S Braunstein, R N Germain

J Exp Med (1986) 163 (3): 678–696.

https://doi.org/10.1084/jem.163.3.678

Published: 01 March 1986

View article titled, I-A-restricted T cell antigen recognition. Analysis of the roles of A alpha and A beta using DNA-mediated gene transfer.

NARROW

Evidence that binding site occupancy is necessary and sufficient for effective major histocompatibility complex (MHC) class II transport through the secretory pathway redefines the primary function of class II-associated invariant chain peptides (CLIP).

Partial signaling by CD8+ T cells in response to antagonist ligands.

Inhibition of invariant chain (Ii)-calnexin interaction results in enhanced degradation of Ii but does not prevent the assembly of alpha beta Ii complexes.

Involvement of both major histocompatibility complex class II alpha and beta chains in CD4 function indicates a role for ordered oligomerization in T cell activation.

Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis.

The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancy.

CD28-mediated costimulation of interleukin 2 (IL-2) production plays a critical role in T cell priming for IL-4 and interferon gamma production.

Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression.

Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signaling.

Relationship between invariant chain expression and major histocompatibility complex class II transport into early and late endocytic compartments.

Serum angiotensin-1 converting enzyme activity processes a human immunodeficiency virus 1 gp160 peptide for presentation by major histocompatibility complex class I molecules.

Presentation of antigen by mixed isotype class II molecules in normal H-2d mice.

Defective intracellular transport as a common mechanism limiting expression of inappropriately paired class II major histocompatibility complex alpha/beta chains.

An immunodominant class I-restricted cytotoxic T lymphocyte determinant of human immunodeficiency virus type 1 induces CD4 class II-restricted help for itself.

Structural requirements for class I MHC molecule-mediated antigen presentation and cytotoxic T cell recognition of an immunodominant determinant of the human immunodeficiency virus envelope protein.

The contribution of mutant amino acids to alloantigenicity.

Surface expression of only gamma delta and/or alpha beta T cell receptor heterodimers by cells with four (alpha, beta, gamma, delta) functional receptor chains.

Early genetic events in T cell development analyzed by in situ hybridization.

Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain.

I-A-restricted T cell antigen recognition. Analysis of the roles of A alpha and A beta using DNA-mediated gene transfer.

Email alerts

Email alerts

This Feature Is Available To Subscribers Only