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Journal Articles

Evidence inconsistent with a role for the Bcg gene (Nramp1) in resistance of mice to infection with virulent Mycobacterium tuberculosis.

E Medina, R J North

J Exp Med (1996) 183 (3): 1045–1051.

https://doi.org/10.1084/jem.183.3.1045

Published: 01 March 1996

View article titled, Evidence inconsistent with a role for the Bcg gene (Nramp1) in resistance of mice to infection with virulent Mycobacterium tuberculosis.

Journal Articles

Neutrophils are essential for early anti-Listeria defense in the liver, but not in the spleen or peritoneal cavity, as revealed by a granulocyte-depleting monoclonal antibody.

J W Conlan, R J North

J Exp Med (1994) 179 (1): 259–268.

https://doi.org/10.1084/jem.179.1.259

Published: 01 January 1994

View article titled, Neutrophils are essential for early anti-Listeria defense in the liver, but not in the spleen or peritoneal cavity, as revealed by a granulocyte-depleting monoclonal antibody.

Journal Articles

Mycobacterial virulence. Virulent strains of Mycobacteria tuberculosis have faster in vivo doubling times and are better equipped to resist growth-inhibiting functions of macrophages in the presence and absence of specific immunity.

R J North, A A Izzo

J Exp Med (1993) 177 (6): 1723–1733.

https://doi.org/10.1084/jem.177.6.1723

Published: 01 June 1993

View article titled, Mycobacterial virulence. Virulent strains of Mycobacteria tuberculosis have faster in vivo doubling times and are better equipped to resist growth-inhibiting functions of macrophages in the presence and absence of specific immunity.

Journal Articles

Evidence for an alpha/beta T cell-independent mechanism of resistance to mycobacteria. Bacillus-Calmette-Guerin causes progressive infection in severe combined immunodeficient mice, but not in nude mice or in mice depleted of CD4+ and CD8+ T cells.

A A Izzo, R J North

J Exp Med (1992) 176 (2): 581–586.

https://doi.org/10.1084/jem.176.2.581

Published: 01 August 1992

View article titled, Evidence for an alpha/beta T cell-independent mechanism of resistance to mycobacteria. Bacillus-Calmette-Guerin causes progressive infection in severe combined immunodeficient mice, but not in nude mice or in mice depleted of CD4+ and CD8+ T cells.

Journal Articles

Neutrophil-mediated dissolution of infected host cells as a defense strategy against a facultative intracellular bacterium.

J W Conlan, R J North

J Exp Med (1991) 174 (3): 741–744.

https://doi.org/10.1084/jem.174.3.741

Published: 01 September 1991

View article titled, Neutrophil-mediated dissolution of infected host cells as a defense strategy against a facultative intracellular bacterium.

Journal Articles

Glucocorticoid-mediated inhibition of endotoxin-induced intratumor tumor necrosis factor production and tumor hemorrhagic necrosis and regression.

R J North, E A Havell

J Exp Med (1989) 170 (3): 703–710.

https://doi.org/10.1084/jem.170.3.703

Published: 01 September 1989

View article titled, Glucocorticoid-mediated inhibition of endotoxin-induced intratumor tumor necrosis factor production and tumor hemorrhagic necrosis and regression.

Journal Articles

Exacerbation of murine listeriosis by a monoclonal antibody specific for the type 3 complement receptor of myelomonocytic cells. Absence of monocytes at infective foci allows Listeria to multiply in nonphagocytic cells.

H Rosen, S Gordon, R J North

J Exp Med (1989) 170 (1): 27–37.

https://doi.org/10.1084/jem.170.1.27

Published: 01 July 1989

View article titled, Exacerbation of murine listeriosis by a monoclonal antibody specific for the type 3 complement receptor of myelomonocytic cells. Absence of monocytes at infective foci allows Listeria to multiply in nonphagocytic cells.

Journal Articles

Elimination of CD4+ suppressor T cells from susceptible BALB/c mice releases CD8+ T lymphocytes to mediate protective immunity against Leishmania.

J O Hill, M Awwad, R J North

J Exp Med (1989) 169 (5): 1819–1827.

https://doi.org/10.1084/jem.169.5.1819

Published: 01 May 1989

View article titled, Elimination of CD4+ suppressor T cells from susceptible BALB/c mice releases CD8+ T lymphocytes to mediate protective immunity against Leishmania.

Journal Articles

Immunologically mediated regression of a murine lymphoma after treatment with anti-L3T4 antibody. A consequence of removing L3T4+ suppressor T cells from a host generating predominantly Lyt-2+ T cell-mediated immunity.

M Awwad, R J North

J Exp Med (1988) 168 (6): 2193–2206.

https://doi.org/10.1084/jem.168.6.2193

Published: 01 December 1988

View article titled, Immunologically mediated regression of a murine lymphoma after treatment with anti-L3T4 antibody. A consequence of removing L3T4+ suppressor T cells from a host generating predominantly Lyt-2+ T cell-mediated immunity.

Journal Articles

Interleukin 1-induced, T cell-mediated regression of immunogenic murine tumors. Requirement for an adequate level of already acquired host concomitant immunity.

R J North, R H Neubauer, J J Huang, R C Newton, S E Loveless

J Exp Med (1988) 168 (6): 2031–2043.

https://doi.org/10.1084/jem.168.6.2031

Published: 01 December 1988

View article titled, Interleukin 1-induced, T cell-mediated regression of immunogenic murine tumors. Requirement for an adequate level of already acquired host concomitant immunity.

Journal Articles

The antitumor function of tumor necrosis factor (TNF) II. Analysis of the role of endogenous TNF in endotoxin-induced hemorrhagic necrosis and regression of an established sarcoma.

R J North, E A Havell

J Exp Med (1988) 167 (3): 1086–1099.

https://doi.org/10.1084/jem.167.3.1086

Published: 01 March 1988

View article titled, The antitumor function of tumor necrosis factor (TNF) II. Analysis of the role of endogenous TNF in endotoxin-induced hemorrhagic necrosis and regression of an established sarcoma.

Journal Articles

The antitumor function of tumor necrosis factor (TNF), I. Therapeutic action of TNF against an established murine sarcoma is indirect, immunologically dependent, and limited by severe toxicity.

E A Havell, W Fiers, R J North

J Exp Med (1988) 167 (3): 1067–1085.

https://doi.org/10.1084/jem.167.3.1067

Published: 01 March 1988

View article titled, The antitumor function of tumor necrosis factor (TNF), I. Therapeutic action of TNF against an established murine sarcoma is indirect, immunologically dependent, and limited by severe toxicity.

Journal Articles

Radiation-induced, immunologically mediated regression of an established tumor as an example of successful therapeutic immunomanipulation. Preferential elimination of suppressor T cells allows sustained production of effector T cells.

R J North

J Exp Med (1986) 164 (5): 1652–1666.

https://doi.org/10.1084/jem.164.5.1652

Published: 01 November 1986

View article titled, Radiation-induced, immunologically mediated regression of an established tumor as an example of successful therapeutic immunomanipulation. Preferential elimination of suppressor T cells allows sustained production of effector T cells.

Journal Articles

T cell suppressors of antitumor immunity. The production of Ly-1-,2+ suppressors of delayed sensitivity precedes the production of suppressors of protective immunity.

A DiGiacomo, R J North

J Exp Med (1986) 164 (4): 1179–1192.

https://doi.org/10.1084/jem.164.4.1179

Published: 01 October 1986

View article titled, T cell suppressors of antitumor immunity. The production of Ly-1-,2+ suppressors of delayed sensitivity precedes the production of suppressors of protective immunity.

Journal Articles

Generation and decay of the immune response to a progressive fibrosarcoma. II. Failure to demonstrate postexcision immunity after the onset of T cell-mediated suppression of immunity.

I Bursuker, R J North

J Exp Med (1984) 159 (5): 1312–1321.

https://doi.org/10.1084/jem.159.5.1312

Published: 01 May 1984

View article titled, Generation and decay of the immune response to a progressive fibrosarcoma. II. Failure to demonstrate postexcision immunity after the onset of T cell-mediated suppression of immunity.

Journal Articles

Generation and decay of the immune response to a progressive fibrosarcoma. I. Ly-1+2- suppressor T cells down-regulate the generation of Ly-1-2+ effector T cells.

R J North, I Bursuker

J Exp Med (1984) 159 (5): 1295–1311.

https://doi.org/10.1084/jem.159.5.1295

Published: 01 May 1984

View article titled, Generation and decay of the immune response to a progressive fibrosarcoma. I. Ly-1+2- suppressor T cells down-regulate the generation of Ly-1-2+ effector T cells.

Journal Articles

Expression of passively transferred immunity against an established tumor depends on generation of cytolytic T cells in recipient. Inhibition by suppressor T cells.

C D Mills, R J North

J Exp Med (1983) 157 (5): 1448–1460.

https://doi.org/10.1084/jem.157.5.1448

Published: 01 May 1983

View article titled, Expression of passively transferred immunity against an established tumor depends on generation of cytolytic T cells in recipient. Inhibition by suppressor T cells.

Journal Articles

Non-H-2 restriction of expression of passively transferred delayed sensitivity.

P A Berche, R J North

J Exp Med (1982) 155 (5): 1334–1343.

https://doi.org/10.1084/jem.155.5.1334

Published: 01 May 1982

View article titled, Non-H-2 restriction of expression of passively transferred delayed sensitivity.

Journal Articles

Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells.

R J North

J Exp Med (1982) 155 (4): 1063–1074.

https://doi.org/10.1084/jem.155.4.1063

Published: 01 April 1982

View article titled, Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells.

Journal Articles

T cell-mediated immunosuppression as an obstacle to adoptive immunotherapy of the P815 mastocytoma and its metastases.

E S Dye, R J North

J Exp Med (1981) 154 (4): 1033–1042.

https://doi.org/10.1084/jem.154.4.1033

Published: 01 October 1981

View article titled, T cell-mediated immunosuppression as an obstacle to adoptive immunotherapy of the P815 mastocytoma and its metastases.

NARROW

Evidence inconsistent with a role for the Bcg gene (Nramp1) in resistance of mice to infection with virulent Mycobacterium tuberculosis.

Neutrophils are essential for early anti-Listeria defense in the liver, but not in the spleen or peritoneal cavity, as revealed by a granulocyte-depleting monoclonal antibody.

Mycobacterial virulence. Virulent strains of Mycobacteria tuberculosis have faster in vivo doubling times and are better equipped to resist growth-inhibiting functions of macrophages in the presence and absence of specific immunity.

Evidence for an alpha/beta T cell-independent mechanism of resistance to mycobacteria. Bacillus-Calmette-Guerin causes progressive infection in severe combined immunodeficient mice, but not in nude mice or in mice depleted of CD4+ and CD8+ T cells.

Neutrophil-mediated dissolution of infected host cells as a defense strategy against a facultative intracellular bacterium.

Glucocorticoid-mediated inhibition of endotoxin-induced intratumor tumor necrosis factor production and tumor hemorrhagic necrosis and regression.

Exacerbation of murine listeriosis by a monoclonal antibody specific for the type 3 complement receptor of myelomonocytic cells. Absence of monocytes at infective foci allows Listeria to multiply in nonphagocytic cells.

Elimination of CD4+ suppressor T cells from susceptible BALB/c mice releases CD8+ T lymphocytes to mediate protective immunity against Leishmania.

Immunologically mediated regression of a murine lymphoma after treatment with anti-L3T4 antibody. A consequence of removing L3T4+ suppressor T cells from a host generating predominantly Lyt-2+ T cell-mediated immunity.

Interleukin 1-induced, T cell-mediated regression of immunogenic murine tumors. Requirement for an adequate level of already acquired host concomitant immunity.

The antitumor function of tumor necrosis factor (TNF) II. Analysis of the role of endogenous TNF in endotoxin-induced hemorrhagic necrosis and regression of an established sarcoma.

The antitumor function of tumor necrosis factor (TNF), I. Therapeutic action of TNF against an established murine sarcoma is indirect, immunologically dependent, and limited by severe toxicity.

Radiation-induced, immunologically mediated regression of an established tumor as an example of successful therapeutic immunomanipulation. Preferential elimination of suppressor T cells allows sustained production of effector T cells.

T cell suppressors of antitumor immunity. The production of Ly-1-,2+ suppressors of delayed sensitivity precedes the production of suppressors of protective immunity.

Generation and decay of the immune response to a progressive fibrosarcoma. II. Failure to demonstrate postexcision immunity after the onset of T cell-mediated suppression of immunity.

Generation and decay of the immune response to a progressive fibrosarcoma. I. Ly-1+2- suppressor T cells down-regulate the generation of Ly-1-2+ effector T cells.

Expression of passively transferred immunity against an established tumor depends on generation of cytolytic T cells in recipient. Inhibition by suppressor T cells.

Non-H-2 restriction of expression of passively transferred delayed sensitivity.

Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells.

T cell-mediated immunosuppression as an obstacle to adoptive immunotherapy of the P815 mastocytoma and its metastases.

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