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Patricia A. Darrah
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Journal Articles

Deconvoluting the interplay of innate and adaptive immunity in BCG-induced nonspecific and TB-specific host resistance

Kerry L. Hilligan, Patricia A. Darrah, Robert A. Seder, Alan Sher
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (4): e20240496.
https://doi.org/10.1084/jem.20240496
Published: 18 March 2025
View article titled, Deconvoluting the interplay of innate and adaptive immunity in BCG-induced nonspecific and TB-specific host resistance
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Journal Articles

Intravenous BCG-mediated protection against tuberculosis requires CD4+ T cells and CD8α+ lymphocytes

Andrew W. Simonson, Joseph J. Zeppa, Allison N. Bucsan, Michael C. Chao, Supriya Pokkali, Forrest Hopkins, Michael R. Chase, Andrew J. Vickers, Matthew S. Sutton, Caylin G. Winchell, Amy J. Myers, Cassaundra L. Ameel, Ryan J. Kelly, Ben Krouse, Luke E. Hood, Jiaxiang Li, Chelsea C. Lehman, Megha Kamath, Jaime Tomko, Mark A. Rodgers, Rachel Donlan, Harris Chishti, H. Jacob Borish, Edwin Klein, Charles A. Scanga, Sarah M. Fortune, Philana Ling Lin, Pauline Maiello, Mario Roederer, Patricia A. Darrah, Robert A. Seder, JoAnne L. Flynn
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (4): e20241571.
https://doi.org/10.1084/jem.20241571
Published: 06 February 2025
View article titled, Intravenous BCG-mediated protection against tuberculosis requires CD4+ T cells and CD8α+ lymphocytes
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Includes: Supplementary data
Journal Articles

IL-10 production differentially influences the magnitude, quality, and protective capacity of Th1 responses depending on the vaccine platform

Patricia A. Darrah, Sonia T. Hegde, Dipti T. Patel, Ross W. B. Lindsay, Linda Chen, Mario Roederer, Robert A. Seder
Journal: Journal of Experimental Medicine
J Exp Med (2010) 207 (7): 1421–1433.
https://doi.org/10.1084/jem.20092532
Published: 07 June 2010
View article titled, IL-10 production differentially influences the magnitude, quality, and protective capacity of Th1 responses depending on the vaccine platform
Open the PDF for IL-10 production differentially influences the magnitude, quality, and protective capacity of Th1 responses depending on the vaccine platform in another window
Includes: Supplementary data
Journal Articles

Dendritic Cells Are Responsible for the Capacity of CpG Oligodeoxynucleotides to Act as an Adjuvant for Protective Vaccine Immunity Against Leishmania major in Mice

Javeed A. Shah, Patricia A. Darrah, David R. Ambrozak, Tara N. Turon, Susana Mendez, Joanna Kirman, Chang-You Wu, Nicolas Glaichenhaus, Robert A. Seder
Journal: Journal of Experimental Medicine
J Exp Med (2003) 198 (2): 281–291.
https://doi.org/10.1084/jem.20030645
Published: 21 July 2003
View article titled, Dendritic Cells Are Responsible for the Capacity of CpG Oligodeoxynucleotides to Act as an Adjuvant for Protective Vaccine Immunity Against Leishmania major in Mice
Open the PDF for Dendritic Cells Are Responsible for the Capacity of CpG Oligodeoxynucleotides to Act as an Adjuvant for Protective Vaccine Immunity Against Leishmania major in Mice in another window